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Table 3 Comparison of threshold filtering of miRNA hairpins with the L-score classifier

From: In silico miRNA prediction in metazoan genomes: balancing between sensitivity and specificity

Method Sensitivity % (number) Specificity % (number) Selectivityc L scorea
Threshold filtering 56.8 (2,216) 99.57 (15,049) 133 -
Scoring model Metazoa     
   Fixed at specificity 62.0 (2,421) 99.57 (15,048) 145 0.221
   Fixed at sensitivity 56.8 (2,216) 99.64 (12,829) 156 0.280
  1. a Sensitivity measured on the taxonomic set Metazoa (3,902 miRNA hairpins)
  2. b Specificity measured on the set of 3,526,115 genomic hairpins in C. elegans
  3. c Selectivity calculated with sensitivity on metazoan miRNAs and specificity measured on C. elegans genomic hairpins
  4. d minimal L score of the scoring model Metazoa for which the performance of threshold filtering performance is equalled