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Table 3 Comparison of threshold filtering of miRNA hairpins with the L-score classifier

From: In silico miRNA prediction in metazoan genomes: balancing between sensitivity and specificity

Method

Sensitivity

% (number)

Specificity

% (number)

Selectivityc

L scorea

Threshold filtering

56.8 (2,216)

99.57 (15,049)

133

-

Scoring model Metazoa

    

   Fixed at specificity

62.0 (2,421)

99.57 (15,048)

145

0.221

   Fixed at sensitivity

56.8 (2,216)

99.64 (12,829)

156

0.280

  1. a Sensitivity measured on the taxonomic set Metazoa (3,902 miRNA hairpins)
  2. b Specificity measured on the set of 3,526,115 genomic hairpins in C. elegans
  3. c Selectivity calculated with sensitivity on metazoan miRNAs and specificity measured on C. elegans genomic hairpins
  4. d minimal L score of the scoring model Metazoa for which the performance of threshold filtering performance is equalled
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BMC Genomics

ISSN: 1471-2164

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