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Figure 1 | BMC Genomics

Figure 1

From: Distinct gene-expression profiles characterize mammary tumors developed in transgenic mice expressing constitutively active and C-terminally truncated variants of STAT5

Figure 1

Principal component analysis (PCA) and unsupervised hierarchical clustering into distinct tumor genotypes. Mammary carcinomas and papillary adenocarcinomas were developed in transgenic mice expressing constitutively activated STAT5 (STAT5ca) or truncated STAT5 (STAT5Δ750). PCA (A) and unsupervised hierarchical clustering (standard correlation, B) were performed on genes that were expressed at significantly (P < 0.05; twofold) different levels in tumors induced by the two STAT5 variants. Both analyses confirmed their distinction based on the transgenic STAT5 variant carried by the host female.

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BMC Genomics

ISSN: 1471-2164

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