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Figure 2 | BMC Genomics

Figure 2

From: Distinct gene-expression profiles characterize mammary tumors developed in transgenic mice expressing constitutively active and C-terminally truncated variants of STAT5

Figure 2

Unsupervised hierarchical clustering of genes that are differentially expressed in tumors induced by STAT5ca and STAT5Δ750 transgenes. Genes with statistically significant (P < 0.05), over twofold differences in expression levels between the two sets of tumors were clustered. In each cluster, cellular processes were annotated. The normalized intensity values indicate relative expression levels compared to the median gene expression in the intact mammary gland ("1"). Arrows mark genes that are specifically affected by STAT5ca (gray) or STAT5Δ750 (black) and listed in Table 2.

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