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Table 1 Repertoire of tRNA genes and codon usage in Tritryps.

From: Gene organization and sequence analyses of transfer RNA genes in Trypanosomatid parasites

Amino acid Codon tDNA anticodon L. major gene copy number T. brucei gene copy number T. cruzi gene copy number Anticodon2 L. major Codon usage % T. brucei Codon usage % T. cruzi Codon usage %
Ala GCT AGC 2 2 2 (98%) 1 IGC 1.83 2.08 1.61
  GCC GGC 0 0 0   3.61 1.82 1.62
  GCA TGC 1 1 2 (97%)1 UGC 2.02 2.32 2.16
  GCG CGC 2 2 (97%) 1 2 CGC 3.62 2.07 2.36
Arg CGT ACG 4 3 4 (98%) 1 ICG 1.05 1.59 1.60
  CGC GCG 0 0 0   3.18 1.45 1.75
  CGA TCG 1 1 2 UCG 0.73 0.9 1.58
  CGG CCG 1 1 2 CCG 1.38 1.21 1.85
  AGA TCT 1 1 2 UCU 0.27 0.68 1.56
  AGG CCT 1 1 2 CCU 0.55 1 1.86
Asn AAT ATT 0 0 0 GUU 0.53 1.82 1.37
  AAC GTT 3 2 4   2.07 1.92 1.45
Asp GAC GTC 3 2 2 GUC 3.42 2.27 1.60
  GAT ATC 0 0 0   1.44 2.81 1.57
Cys TGT ACA 0 0 0 GCA 0.42 1.09 1.78
  TGC GCA 1 2 2   1.46 1.13 2.34
Gln CAA TTG 1 1 2 UUG 0.76 1.69 1.66
  CAG CTG 3 2 4 CUG 3.32 2.1 1.8
Glu GAA TTC 1 1 1 UUC 1.14 3.17 2.17
  GAG CTC 2 2 4 (95%) 1 CUC 3.32 3.81 2.21
Gly GGT ACC 0 0 0 GCC 1.25 2.27 1.51
  GGC GCC 4 3 4   3.36 1.49 1.95
  GGA TCC 1 1 2 UCC 0.64 1.56 2.16
  GGG CCC 1 1 2 CCC 1.19 1.39 1.64
His CAT ATG 0 0 0 GUG 0.65 1.13 1.37
  CAC GTG 2 1 4 (98%) 1   2.04 1.3 1.64
Ile ATT AAT 3 2 4 IAU 0.82 1.9 1.42
  ATC GAT 0 0 0   1.88 1.16 1.10
  ATA TAT 1 1 2 UAU 0.27 1 0.75
Leu TTA TAA 1 1 2 UAA 0.16 0.98 0.89
  TTG CAA 1 1 2 CAA 1.1 1.96 2.33
  CTT AAG 3 1 4 IAG 1.11 2.23 1.59
  CTC GAG 0 0 0   2.5 1.56 1.27
  CTA TAG 1 1 2 UAG 0.47 0.82 0.54
  CTG CAG 2 1 2 CAG 3.83 1.85 1.95
Lys AAA TTT 1 1 2 UUU 0.54 2.06 1.94
  AAG CTT 3 3 4 CUU 2.78 2.66 1.88
Met ATG CAT 4 3 6 CAU 2.25 2.34 2.12
Phe TTT AAA 0 0 0 GAA 1.04 2.05 2.17
  TTC GAA 2 2 4   1.91 1.59 1.49
Pro CCT AGG 2 1 2 IGG 0.86 1.11 1.05
  CCC GGG 0 0 0   1.24 1.11 1.03
  CCA TGG 1 1 2 UGG 1.05 1.39 1.44
  CCG CGG 2 1 2 CGG 2.61 1.18 1.57
Ser TCT AGA 1 1 2 IGA 1.02 1.26 1.37
  TCC GGA 0 0 0   1.69 1.25 1.24
  TCA TGA 1 1 2 (98%) 1 UGA 0.73 1.35 1.41
  TCG CGA 1 1 2 CGA 2.17 1.16 1.2
  AGT ACT 0 0 0 GCU 0.73 1.51 1.21
  AGC GCT 2 (98%) 1 2 2   2.6 1.35 1.60
Thr ACT AGT 3 1 2 IGU 0.68 1.3 1.13
  ACC GGT 0 0 0   1.77 1.21 1.18
  ACA TGT 1 1 2 UGU 1.04 1.74 1.74
  ACG CGT 2 1 2 CGU 2.48 1.48 1.98
Trp TGG CCA 1 1 2 CCA 1.07 1.09 2.33
Tyr TAT ATA 0 0 0 GUA 0.4 1.13 0.84
  TAC GTA 3 1 2   1.99 1.41 1.04
Val GTT AAC 2 2 2 IAC 0.86 2.29 1.49
  GTC GAC 0 0 0   1.92 1.14 1.26
  GTA TAC 1 1 2 UAC 0.54 1.26 0.83
  GTG CAC 2 1 1 CAC 3.82 2.87 2.65
SeC TGA TCA 1 2 8     
TOTAL    83 66 120     
  1. 1 One isodecoder tRNA was identified in L. major, one in T. brucei and six in T. cruzi. The percentage of identity between isodecoders is shown between parentheses. The rest of the genes with the same anticodon are 100% identical.
  2. 2 Underlined anticodons are those that recognize more than one codon; for exemple, the Tyr anticodon GUA recognizes two codons, TAT and TAC, since anticodon Tyr-AUA is missing in trypanosomatids. A1 of the anticodon is modified to inosine (I).