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Table 4 Gene models modified by FcB1-schizont-ESTs.

From: A Plasmodium falciparum FcB1-schizont-EST collection providing clues to schizont specific gene structure and polymorphism

[Gene] (a)

[Product Description] (b)

[Pf-iRBC max expr time (GS array)] (c)

[Pf-iRBC+Spz+Gam max expr stage (Affy)] (d)

# of ESTs (e)

modified in gene model (f)

PFA0630c

hypothetical protein

16

Early Trophozoite

17

in agreement with chr1.genefinder_16r, chr1.glimmerm_366 and chr1.phat_146 *

MAL13P1.460

conserved hypothetical protein

  

77

intron 3 modified

MAL8P1.73

hypothetical protein, conserved

40

Early Schizogony

28

intron 16 modified but intron 18 confirmed

PF10_0072

hypothetical protein

 

Late Schizogony

8

exon 1 would be longer at 3' end

PF10_0361

hypothetical protein

23

Early Ring

37

in agreement with chr11, glimmer_1141

PF11_0194

hypothetical protein

41

Gametocyte

50

in agreement with chr11, genefinder.157r *

PF13_0193

MSP7-like protein

 

Early Schizogony

41

exon 1 would be longer at 3' end

PF14_0280

phosphotyrosyl phosphatase activator, putative

20

Gametocyte

2

gene would be longer downstream

PFB0305c

merozoite surface protein 5

46

Late Schizogony

5

exon 2 would be longer at 5' end

PFE0240w

hypothetical protein, conserved

 

Gametocyte

12

four additional exons, longer protein *

PFE1490c

hypothetical protein, conserved

 

Early Ring

16

intron 1 modified but intron 2 confirmed

PFI0905w

hypothetical protein

 

Gametocyte

4

exon 2 would be longer at 5' end **

PFI1565w

conserved protein

 

Late Schizogony

11

3'-end of gene in agreement with chr9.glimmerm_973 and chr9.glimmerm_974 *

PFL0290w

hypothetical protein, conserved

43

Early Trophozoite

11

intron 1 modified but intron 2 confirmed *

  1. This table, derived from Additional file 1, lists the 14 P. falciparum genes whose gene models were corrected based on FcB1-schizont-ESTs. Columns (a) to (e) are as described in the Table 3 legend. The last column (f) details each modification. Note that three genes in this list were both modified/confirmed (in different parts): MAL8P1.73, PFE1490c and PFL0290w. Asterisks (*) in this last column refer to examples illustrated in Additional file 4. The model revision proposed for PFI0905w (**) will need to be confirmed by other experimental data since these 4 ESTs also matched P. falciparum telomerase RNA (see Additional file 10). Pf-iRBC, P. falciparum-infected red blood cells.