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Table 5 Evidence of protein polymorphism between FcB1 and 3D7 strains.

From: A Plasmodium falciparum FcB1-schizont-EST collection providing clues to schizont specific gene structure and polymorphism

[Gene] (a)

[Product Description] (b)

[Pf-iRBC max expr time (GS array)] (c)

[Pf-iRBC+Spz+Gam max expr stage (Affy)] (d)

# of ESTs (e)

type of polymorphism (f)

PFA0215w

hypothetical protein, conserved

45

Late Schizogony

72

in tandem repeats

PFD0185c

peptidase

42

Gametocyte

10

in tandem repeats

PFE0250w

hypothetical protein, conserved

25

Early Trophozoite

39

in Asn-rich region

PFE0655w

hypothetical protein, conserved

16

Early Trophozoite

2

in tandem repeats

PFF0670w

hypothetical protein, conserved

38

 

47

in Asn-rich region

PFF0765c

hypothetical protein, conserved

41

 

3

in tandem repeats

MAL7P1.208

rhoptry-associated membrane antigen, RAMA

41

 

147

in tandem repeats

PF07_0111

hypothetical protein, conserved

37

Gametocyte

1

in tandem repeats

PF08_0109

hypothetical protein, conserved

39

Early Schizogony

5

in Asn-rich region

PF10_0177

erythrocyte membrane-associated antigen

40

Gametocyte

31

in tandem repeats

PF10_0184

hypothetical protein

41

Gametocyte

13

local polymorphism

PF10_0213

10b antigen, putative

33

Early Schizogony

20

in Asn-rich region

PF10_0345

merozoite surface protein 3

42

Late Schizogony

93

mild polymorphism

PF10_0351

hypothetical protein

45

Late Schizogony

83

in tandem repeats

PFL0465c

Zinc finger transcription factor (krox1)

 

Late Schizogony

1

mild polymorphism

PFL1385c

Merozoite Surface Protein 9, MSP-9

41

Early Schizogony

310

mild polymorphism

PF13_0053

hypothetical protein, conserved

12

Early Trophozoite

52

in tandem repeats

MAL13P1.158

hypothetical protein, conserved

40

Gametocyte

10

local polymorphism

PF13_0245

hypothetical protein, conserved

46

Early Trophozoite

16

mild polymorphism

PF14_0175

conserved protein unknown function

  

107

in tandem repeats

PF14_0486

elongation factor 2

17

Early Trophozoite

5

mild polymorphism

  1. This table, derived from Additional file 1, lists the 21 P. falciparum genes for which some protein polymorphism was identified between FcB1 and 3D7 strains. Columns (a) to (e) are as described in the Table 3 legend. The last column (f) details the various cases. All protein sequence alignments are illustrated in Additional file 5. Pf-iRBC, P. falciparum-infected red blood cells.