Figure 1

Schematic representation and intra -exon nucleotide variations of DDX11L gene family members. (A) On the top. DDX11L genomic localization between WASH genes and the telomeric repeats. White arrows indicate the sense of gene transcription. Grey boxes represent the exons of DDX11L genes. Numbers indicate the exon boundaries. On the bottom. DDX11L alternative spliced transcript of 1481 bp, in the chromosomes 15, 17 and 19. ATG is located in position 317 and the TAG stop codon in position 718. This transcript shows a significant ORF of 402 bp, encoding a putative protein of 133 aa. (B) Positions of nucleotide variations referred to X chromosome cDNA. Asterisks and underlined nucleotides represent deletion/insertion sites.