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Table 1 List of differentially expressed genes classified into G protein dependent signaling and related functional groups

From: Transcriptional analysis of the mammalian heart with special reference to its endocrine function

Functional Group/Probe set ID Gene Description Fold change
G Protein signaling
1369740_at Potassium inwardly-rectifying channel, subfamily J, member 3 7.76
1368560_at Potassium inwardly-rectifying channel, subfamily J, member 5 7.68
1369741_at Potassium inwardly-rectifying channel, subfamily J, member 3 6.35
1369273_a_at Natriuretic peptide receptor 3 6.02
1396249_at Natriuretic peptide receptor 3 4.06
1387803_at Protein phosphatase 2, regulatory subunit B, beta isoform 3.94
1367920_at Endothelial differentiation, sphingolipid G-protein-coupled receptor, 5 3.27
1367791_at Receptor (calcitonin) activity modifying protein 1 3.05
1392905_at Guanine nucleotide binding protein, gamma 2 2.74
1368879_a_at Guanine nucleotide binding protein, alpha o 2.31
1369377_at Hypocretin receptor 2 2.00
1373202_at Guanine nucleotide binding protein, gamma 3 1.96
1369647_at Calcitonin receptor-like -1.82
1369115_at Adrenergic receptor, beta 2 -1.83
1368660_at cAMP-regulated guanine nucleotide exchange factor I -1.93
1388109_at G protein-coupled hepta-helical receptor Ig-Hepta -1.95
1370449_at G protein-coupled receptor 105 -2.20
1368534_at Adrenergic receptor, alpha 1d -2.34
1398530_at guanine nucleotide binding protein (G protein), gamma 11 -2.34
1368300_at Adenosine A2a receptor -2.46
1370522_at Glucagon receptor -3.07
1395473_at Guanine nucleotide binding protein, beta 3 -3.65
1387671_at Secretin receptor -4.31
Accessory proteins for G proteins
1391187_at Periplakin (predicted) 4.23
1387908_at RAS, dexamethasone-induced 1 (Rasd1/AGS1) 3.75
1377390_at Beta-site APP-cleaving enzyme 2 3.54
1387074_at Regulator of G-protein signaling 2 2.61
1379517_at Regulator of G-protein signaling 6 2.47
1369957_at Regulator of G-protein signaling 5 -2.33
1370372_at RASD family, member 2 -3.32
1372383_at G-protein signaling modulator 1 (AGS3-like, C. elegans) -11.43
Neuropeptide signaling pathway
1367992_at Secretory granule neuroendocrine protein 1 3.20
1382967_at G protein-coupled receptor 64 2.50
1369377_at Hypocretin receptor 2 2.00
1368428_at X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound -1.99
1371696_at G protein-coupled receptor 56 -2.16
1367949_at Preproenkephalin -13.55
Serotonin receptor signaling
1369125_at 5-hydroxytryptamine (serotonin) receptor 2A 7.84
1369124_at 5-hydroxytryptamine (serotonin) receptor 2A 1.88
  1. Positive fold change values indicate a higher abundance in the atria as compared to the ventricles, while negative fold change values demonstrate a higher ventricular abundance in comparison to the atria.