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Table 1 List of differentially expressed genes classified into G protein dependent signaling and related functional groups

From: Transcriptional analysis of the mammalian heart with special reference to its endocrine function

Functional Group/Probe set ID

Gene Description

Fold change

G Protein signaling

1369740_at

Potassium inwardly-rectifying channel, subfamily J, member 3

7.76

1368560_at

Potassium inwardly-rectifying channel, subfamily J, member 5

7.68

1369741_at

Potassium inwardly-rectifying channel, subfamily J, member 3

6.35

1369273_a_at

Natriuretic peptide receptor 3

6.02

1396249_at

Natriuretic peptide receptor 3

4.06

1387803_at

Protein phosphatase 2, regulatory subunit B, beta isoform

3.94

1367920_at

Endothelial differentiation, sphingolipid G-protein-coupled receptor, 5

3.27

1367791_at

Receptor (calcitonin) activity modifying protein 1

3.05

1392905_at

Guanine nucleotide binding protein, gamma 2

2.74

1368879_a_at

Guanine nucleotide binding protein, alpha o

2.31

1369377_at

Hypocretin receptor 2

2.00

1373202_at

Guanine nucleotide binding protein, gamma 3

1.96

1369647_at

Calcitonin receptor-like

-1.82

1369115_at

Adrenergic receptor, beta 2

-1.83

1368660_at

cAMP-regulated guanine nucleotide exchange factor I

-1.93

1388109_at

G protein-coupled hepta-helical receptor Ig-Hepta

-1.95

1370449_at

G protein-coupled receptor 105

-2.20

1368534_at

Adrenergic receptor, alpha 1d

-2.34

1398530_at

guanine nucleotide binding protein (G protein), gamma 11

-2.34

1368300_at

Adenosine A2a receptor

-2.46

1370522_at

Glucagon receptor

-3.07

1395473_at

Guanine nucleotide binding protein, beta 3

-3.65

1387671_at

Secretin receptor

-4.31

Accessory proteins for G proteins

1391187_at

Periplakin (predicted)

4.23

1387908_at

RAS, dexamethasone-induced 1 (Rasd1/AGS1)

3.75

1377390_at

Beta-site APP-cleaving enzyme 2

3.54

1387074_at

Regulator of G-protein signaling 2

2.61

1379517_at

Regulator of G-protein signaling 6

2.47

1369957_at

Regulator of G-protein signaling 5

-2.33

1370372_at

RASD family, member 2

-3.32

1372383_at

G-protein signaling modulator 1 (AGS3-like, C. elegans)

-11.43

Neuropeptide signaling pathway

1367992_at

Secretory granule neuroendocrine protein 1

3.20

1382967_at

G protein-coupled receptor 64

2.50

1369377_at

Hypocretin receptor 2

2.00

1368428_at

X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound

-1.99

1371696_at

G protein-coupled receptor 56

-2.16

1367949_at

Preproenkephalin

-13.55

Serotonin receptor signaling

1369125_at

5-hydroxytryptamine (serotonin) receptor 2A

7.84

1369124_at

5-hydroxytryptamine (serotonin) receptor 2A

1.88

  1. Positive fold change values indicate a higher abundance in the atria as compared to the ventricles, while negative fold change values demonstrate a higher ventricular abundance in comparison to the atria.