Figure 3
Comparison of differential transcription according to functional class – specific responses. The number of differentially regulated transcripts within each functional class is expressed as a percentage of the total number transcripts detected in hemocytes for each experimental comparison. (a) The percentage of genes, for each functional class, expressed in hemocytes which were differentially regulated following either bacterial challenge and/or malaria parasite infection. Dashed line indicates the overall percentage of each functional class in the differentially expressed genes in hemocytes; this percentage of transcripts is expected to be differentially expressed within each functional class if there is no association between functional class and differential transcription. Functional classes exhibiting significant over- or under-representation among expressed transcripts are indicated by asterisks (χ2-test; see main text for details). (b) The same as (a) but for each challenge. IMM = immunity-and apoptosis-related; RED/STE = redox/stress/mitochondrial; PROT = proteolysis; CYT/STR = cytoskeletal/structural; TRP = transporters; MET = metabolism; R/T/T = replication/transcription/translation; DIV = diverse; and UNK = unknown.