Figure 3From: Epistatic interactions modulate the evolution of mammalian mitochondrial respiratory complex componentsMolecular mechanism of compensation at CYB. (A) Human CYB model highlighting the Gly251 residue and all putative compensatory sites [see Additional file 1]. (B) Transmembrane structure with the deleterious residue highlighted and comparison of human wild-type sequence with non-human carriers of the deleterious Ser251 (red) and compensatory Pro258 and Ser263 partners (blue).Back to article page