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Figure 3 | BMC Genomics

Figure 3

From: Epistatic interactions modulate the evolution of mammalian mitochondrial respiratory complex components

Figure 3

Molecular mechanism of compensation at CYB. (A) Human CYB model highlighting the Gly251 residue and all putative compensatory sites [see Additional file 1]. (B) Transmembrane structure with the deleterious residue highlighted and comparison of human wild-type sequence with non-human carriers of the deleterious Ser251 (red) and compensatory Pro258 and Ser263 partners (blue).

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