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Table 4 Major known genes by functional class in the L3i gene set

From: Transcriptomes and pathways associated with infectivity, survival and immunogenicity in Brugia malayi L3

Functional class Gene Oligo ID Fold NCBI accession number and description
Immunomodulators alt-1 BMC00123 35 AAB03902.2| Av18, Alt 1 variant
  alt-2 (2) 14863.m00021 20 AAF01224.1| Alt2 variant
  cpi-1 (3) BMC12220 41 AAD51085.1| cystatin-type cysteine proteinase inhibitor CPI-1
  cpi-2 (2) BMW01194 4 AAD51086.1| cystatin-type cysteine proteinase inhibitor CPI-2
  spn-1 (5) AA840996 20 AAB42377.1| BmSERPIN
Anti-oxidants gst (1) BMC02401 2.6 CAA73325.1| glutathione transferase
detoxification sod (3) BMC00677 2.2 AAR06638.1| superoxide dismutase
  akr (1) AA841533 15.4 NP_509242.1| (Aldo/keto reductase family proteins)
  grx (1) 13358.m00042 4.2 CAE74325.1| Glutaredoxin-like region
  tpx-1 (1) TC2998 11.2 AAN34969.1| thioredoxin 1; ov-thioredoxin 1
  tpx-1 ( 3) BMC12191 2.4 AAL91107.1| thioredoxin
  tpx-2 (1) BMC12241 3.7 Q17172|TDX2hioredoxin peroxidase 2
  trxR (1) 14972.m07078 4.3 AAD46625.1| thioredoxin reductase homolog
  pxn-2 (1) BMC12240 4.3 AAC77922.1| peroxidoxin-2
Proteases cpl-1 ( 7) BMC01348 10.7 AAK16513.1|cathepsin L-like cysteine proteinase
  cpl-4 ( 4) BMC06080 20.8 AAT07057.1| cathepsin L-like cysteine proteinase
  cpl-5 (2) BMC11984 19.7 AAT07058.1| cathepsin L-like cysteine proteinase
  mtp (1) BMC10914 4.6 BAC66058.1| matrix metalloproteinase
Pathogenesis val-1 (7) BMC12291 10 gb|AAB97283.2| vespid allergen antigen homolog
related protein nlt-1 BMC12455 7.5 AAD11970.1| 24 kDa secreted protein
Parasitism ov103 12584.m00062 13.6 AAA63412.2| microfilariae surface-associated
   BMC01088 3.2 AAF76925.1|1 hypothetical esophageal gland cell secretory protein 11
Stress resistant shsp TC3642 10.2 AAB07020.1| small heat shock protein
Cuticular components elo-3 14954.m01636 58.2 ref|NP_501147.2| fatty acid ELOngation family member (elo-3)
Related member col (47) TC2764 11.2 NP_500520.1| COLlagen family member (col-34)
  Grl-4 14083.m00057 8.9 NP_501166.2| GRound-Like (grd related) family member (grl-4)
Highly immunogenic Val (8) BMC12291 9.9 aaB97283.2 vespid allergen antigen homolog
  (3) WB-contig_1280 10.8 AAA63412.2| microfilariae surface-associated
  (1) BMC07029 2.8 P23730|IFEA_ASCSU Intermediate filament protein A
  (3) 14323.m00082 7.1 AAN62757.1| larval allergen [Brugia malayi]
  spx-1 (4) BMC05831 6.1 AAA27864.1| SPX-1
  (2) BMC02375 3.6 AAC48290.1| Gln-rich protein
  1. Numbers in parentheses represent the number of oligos that match a particular gene that was upregulated.