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Table 5 Major known genes by functional class in the L3ir gene set

From: Transcriptomes and pathways associated with infectivity, survival and immunogenicity in Brugia malayi L3

Functional class

Gene

Oligo ID

Fold

NCBI accession number and description

Irradiation responsive

    
 

aid (3)

BMC04376

9.2

CAA62521.1| cytidine deaminase [Brugia pahangi]

 

ada (1)

BMC12015

3

NP_501087.1| C06G3.5a

 

up ase (1)

13555.m00076

11.2

NP_498671.2| ZK783.2 (Uridine phosphorylase)

 

zinc finger protein (1)

BMC11725

2.2

CAA34357.1| zinc finger protein

 

Gated Ion channel (1)

AI856833

5.5

NP_001023062.1| C43F9.9 (Neurotransmitter-gated ion-channel)

 

aqp (2)

BMC02613

2.7

NP_502044.1| AQuaPorin or aquaglyceroporin related family member (aqp-3)

 

Transketolase (1)

BMC06090

3.8

NP_501878.1| F01G10.1 (Transketolase)

Cuticular components Secretory and membrane proteins Immunogenic

    
 

col (64)

BMC03733

4

NP_001040924.1| COLlagen family member (col-14)

  

13970.m00031

3

YP_293890.1| putative membrane protein

  

BMC02058

2.2

NP_500485.1| F49F1.1 (Secreted surface protein)

 

Gln-rich (3)

BMC11922

5.9

AAC48290.1| Gln-rich protein

 

Oveg 1 (2)

BMC05959

4.3

AAB35895.1| Oveg1

 

Juv-p120 (1)

14672.m00017

2.2

AAS92593.1| excretory/secretory protein Juv-p120

 

bmif (1)

BMC07029

3.1

P23730|IFEA_ASCSU Intermediate filament protein A

 

spx-1 (3)

BMC06144

2.3

AAA27864.1| SPX-1

Antioxidant detoxification

    
 

pxn-2 (1)

BMC12240

3

AAC77922.1| peroxidoxin-2

 

tpx-2 (1)

BMC12241

2.8

Q17172|TDX2_BRUMA Thioredoxin peroxidase 2

 

gst (1)

BMC02401

2.3

CAA73325.1| glutathione transferase

 

tpx-1 (1)

TC2998

3.6

AAN34969.1| thioredoxin 1; ov-thioredoxin 1

Fatty acid binding

    
 

scp (1)

TC3583

3.6

XP_392432.2| similar to Sterol carrier protein X

  1. Numbers in parentheses represent the number of oligos that match a particular gene that was upregulated.