Definition, conservation and epigenetics of housekeeping and tissue-enriched genes

BMC Genomics

Table 1 Cross-species conservation of housekeeping genes and tissue enriched genes

	HKG orthologs		TEG orthologs		Orthologs of all genes on array
	Count	Ratio	Count	Ratio	Count	Ratio
Human	1,380	100%	843	100%	17,641	100%
Mouse	1,352	98%	799	95%	16,614	94%
Rat	1,258	91%	763	91%	15,312	87%
Dog	1,287	93%	697	83%	15,127	86%
Fly	752	54%	122	14%	5,111	29%
Worm	639	46%	103	12%	3,973	23%
Yeast	324	23%	20	2%	1,591	9%
P value	0.010		0.065		N/A

The ratio indicates the fraction of human genes with orthologs in other species. 1380, 843 and 17,641 of total HKGs, TEGs and all genes on the array, respectively, are represented in HomoloGene and these numbers were used to calculate the ratio of orthologs.

ISSN: 1471-2164