Table 4 Significant biological processes and pathways from the hepatotoxicant exposures
Identifier | Term | p-value |
|---|---|---|
Correlated with ALT | Â | Â |
GO:0006952 | defense response | 1.15E-04 |
GO:0006928 | cell motility | 8.31E-04 |
GO:0048519 | negative regulation of biological process | 1.09E-03 |
GO:0009605 | response to external stimulus | 1.17E-03 |
GO:0018108 | peptidyl-tyrosine phosphorylation | 1.41E-03 |
GO:0050819 | negative regulation of coagulation | 1.46E-03 |
GO:0018212 | peptidyl-tyrosine modification | 1.69E-03 |
GO:0032496 | response to lipopolysaccharide | 1.80E-03 |
GO:0007626 | locomotory behavior | 1.95E-03 |
GO:0007599 | hemostasis | 2.01E-03 |
GO:0008283 | cell proliferation | 2.05E-03 |
GO:0009611 | response to wounding | 2.06E-03 |
GO:0051707 | response to other organism | 2.15E-03 |
GO:0050818 | regulation of coagulation | 2.19E-03 |
GO:0002237 | response to molecule of bacterial origin | 2.19E-03 |
GO:0051246 | regulation of protein metabolic process | 3.64E-03 |
GO:0042127 | regulation of cell proliferation | 3.91E-03 |
GO:0065008 | regulation of biological quality | 5.76E-03 |
GO:0032501 | multicellular organismal process | 6.25E-03 |
GO:0008284 | positive regulation of cell proliferation | 7.11E-03 |
GO:0048523 | negative regulation of cellular process | 7.16E-03 |
GO:0007596 | blood coagulation | 8.27E-03 |
GO:0050789 | regulation of biological process | 8.48E-03 |
GO:0050878 | regulation of body fluid levels | 8.96E-03 |
GO:0009617 | response to bacterium | 9.56E-03 |
GO:0009607 | response to biotic stimulus | 1.08E-02 |
rno04640 | Hematopoietic cell lineage | 3.00E-02 |
rno04670 | Leukocyte transendothelial migration | 6.96E-02 |
Anti-correlated with ALT | Â | Â |
GO:0006629 | lipid metabolic process | 7.39E-04 |
GO:0032787 | monocarboxylic acid metabolic process | 5.01E-03 |
GO:0008202 | steroid metabolic process | 5.10E-03 |
GO:0008152 | metabolic process | 7.68E-03 |
GO:0042221 | response to chemical stimulus | 7.86E-03 |
rno00960 | Alkaloid biosynthesis II | 2.18E-03 |
rno00380 | Tryptophan metabolism | 1.92E-02 |
rno00920 | Sulfur metabolism | 4.53E-02 |