Table 6 Significant biological processes and pathways discerning isomers and from an early toxic response
Identifier | Term | p-value |
|---|---|---|
Up-regulated | Â | Â |
GO:0009611 | response to wounding | 5.10E-05 |
GO:0001525 | angiogenesis | 6.07E-04 |
GO:0002376 | immune system process | 1.29E-03 |
GO:0009605 | response to external stimulus | 1.33E-03 |
GO:0007596 | blood coagulation | 3.19E-03 |
GO:0042730 | fibrinolysis | 3.56E-03 |
GO:0006954 | inflammatory response | 3.96E-03 |
GO:0030595 | leukocyte chemotaxis | 4.83E-03 |
GO:0006935 | chemotaxis | 4.94E-03 |
GO:0030195 | negative regulation of blood coagulation | 6.00E-03 |
GO:0006873 | cellular ion homeostasis | 6.72E-03 |
GO:0042127 | regulation of cell proliferation | 9.24E-03 |
rno04660 | T cell receptor signaling pathway | 2.91E-02 |
rno04810 | Regulation of actin cytoskeleton | 3.33E-02 |
rno04520 | Adherens junction | 4.58E-02 |
rno04620 | Toll-like receptor signaling pathway | 5.95E-02 |
Down-regulated | Â | Â |
GO:0005975 | carbohydrate metabolic process | 1.89E-04 |
GO:0032787 | monocarboxylic acid metabolic process | 1.06E-03 |
GO:0005978 | glycogen biosynthetic process | 1.82E-03 |
GO:0006066 | alcohol metabolic process | 2.09E-03 |
GO:0000271 | polysaccharide biosynthetic process | 5.09E-03 |
GO:0019318 | hexose metabolic process | 5.68E-03 |
GO:0042593 | glucose homeostasis | 6.71E-03 |
GO:0019752 | carboxylic acid metabolic process | 8.06E-03 |
GO:0006094 | gluconeogenesis | 8.54E-03 |
rno04910 | Insulin signaling pathway | 4.10E-02 |
rno00030 | Pentose phosphate pathway | 9.79E-02 |
Early response | Â | Â |
GO:0006469 | negative regulation of protein kinase activity | 3.82E-06 |
GO:0016070 | RNA metabolic process | 3.88E-04 |
GO:0006355 | regulation of transcription, DNA-dependent | 4.35E-04 |
GO:0012501 | programmed cell death | 6.37E-04 |
GO:0032774 | RNA biosynthetic process | 7.12E-04 |
GO:0031323 | regulation of cellular metabolic process | 1.27E-03 |
GO:0045941 | positive regulation of transcription | 4.03E-03 |
GO:0030154 | cell differentiation | 5.41E-03 |
GO:0006366 | transcription from RNA polymerase II promoter | 9.35E-03 |
rno04010 | MAPK signaling pathway | 2.17E-04 |
rno04012 | ErbB signaling pathway | 2.60E-02 |
rno04912 | GnRH signaling pathway | 2.67E-02 |