Figure 8From: Impact of animal strain on gene expression in a rat model of acute cardiac rejectionValidation of microarray results for genes showing a rejection effect independent of animal strain. Two genes, S100a9 and Gzmb, induced by rejection (Table 1), and 2 genes, Prss1 and Lgals5, suppressed by rejection (Table 2) in peripheral blood mononuclear cells (PBMC) were selected for qRT-PCR. Microarray and qRT-PCR are from the same animals. The rejection effect in PBMC was defined as the strain plus rejection effect divided by the strain effect. Rejection effects on these 4 genes as measured by microarray and qRT-PCR were concordant.Back to article page