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Table 2 Candidate genes suppressed by acute cellular rejection relative to the strain effect in peripheral blood mononuclear cells

From: Impact of animal strain on gene expression in a rat model of acute cardiac rejection

Gene Title

Gene Symbol

Entrez Gene

Strain+Rejection Effect FC

Strain Effect FC

Strain+Rejection /Strain FC

p-value

similar to Glycophorin

LOC688972

688972

0.55

10.07

0.05

8.26E-04

pancreatic trypsin 1

Prss1

24691

0.08

0.91

0.09

3.49E-04

similar to RIKEN cDNA 1110063G11 (predicted)

RGD1311960_predicted

305095

0.09

0.97

0.10

1.09E-04

transcription factor Dp 2 (predicted)

Tcfdp2_predicted

300947

0.22

1.94

0.11

2.53E-03

Translocase of inner mitochondrial membrane 9 homolog (yeast)

Timm9

171139

2.20

17.91

0.12

1.19E-03

lectin, galactose binding, soluble 5

Lgals5

25475

0.18

1.36

0.13

5.55E-04

immunoglobulin heavy chain 1a (serum IgG2a)

Igh-1a

299352

0.46

3.21

0.14

2.19E-03

selenium binding protein 2

Selenbp1

140927

0.20

1.24

0.16

7.24E-03

SNF1-like kinase

Snf1lk

59329

3.31

18.46

0.18

7.67E-03

pre-eosinophil-associated ribonuclease-2

LOC474169

474169

1.15

4.82

0.24

5.67E-05

2,3-bisphosphoglycerate mutase

Bpgm

296973

0.27

1.04

0.26

9.24E-03

unc-5 homolog C (C. elegans)

Unc5c

362049

1.11

3.42

0.32

1.01E-03

  1. The p-value column is derived from a post hoc test that the Strain+Rejection FC/Strain FC is not equal to 1.