Figure 4

Gene Set Enrichment Analysis. Enrichment plot is shown for a set of upregulated genes of a transcriptional profile commonly activated in undifferentiated cancer ("CANCER_UNDIFFERENTIATED_META_UP" as compared to differentiated cancer [22]). The enrichment score (ES, green line) reflects the degree to which the gene set is over-represented at the top or bottom of the ranked list of genes. Black bars illustrate the position of genes belonging to the gene set in the ranked list of genes included in the analysis. The ranked list metric shown in gray measures a gene's correlation with a phenotype. A positive value indicates correlation with "normal female "- phenotype, a negative value with "normal male" – phenotype.