Genome sequence analysis of Helicobacter pylori strains associated with gastric ulceration and gastric cancer

BMC Genomics

Table 2 Highly divergent alleles in East Asian strain 98-10

Gene number (98-10)	Gene number (26695)	Description	% aa identity (98-10)^a	% aa identity (non-98-10) ^b	% unique sites ^c
HP9810_903g20	HP0061^d	Hypothetical	67	86	21
HP9810_889g5	HP0492^d	hpaA homologue	72	92	21
HP9810_889g32	HP0519^d	sel1 homologue	73	92	15
HP9810_905g13	HP0547	cagA	79	87	11
HP9810_868g41	HP0806^d	Hypothetical	86	92	6
HP9810_899g75	HP1322^d	Hypothetical	75	90	18
HP9810_899g76	HP1323^d	Ribonuclease	88	92	6
HP9810_885g15	HP1524^d	Hypothetical	80	95	13

^a The sequences of the indicated gene products in strain 98-10 were compared with corresponding sequences in each of the other 4 strains (26695, J99, HPAG1 and B128), and mean % amino acid identities were calculated as described in Methods.
^b The sequences of the indicated gene products in each strain were compared in all permutations, except that comparisons involving strain 98-10 were excluded from analysis. Mean % amino acid identities were calculated as described in Methods.
^cPercentage of aligned sites in which the protein from strain 98-10 contained an amino acid different from the corresponding amino acids in proteins from 4 other strains.
^dReported to be a constituent of the H. pylori core genome, based on at least one array analysis [18–20].

ISSN: 1471-2164