Figure 3
From: Transcriptomic and proteomic profiling of two porcine tissues using high-throughput technologies
Comparison of differentially expressed genes across transcript-based technologies. Level of agreement between 454-sequencing and cDNA microarray in the direction of regulation for 198 genes identified as significantly (adj. P ≤ 0.05) regulated between heart and skeletal muscle by both technologies. The scatter plot shows the log2 of the ratios between heart and skeletal muscle obtained with 454-sequencing plotted against those obtained with cDNA microarray. Red spots: 113 genes being up-regulated in heart compared to skeletal muscle were identified with both 454-sequencing and cDNA microarray. Green spots: 47 genes being down-regulated in heart compared to skeletal muscle were identified with both 454-sequencing and cDNA microarray. Yellow spots: 6 genes being up-regulated in heart compared to skeletal muscle were identified with cDNA microarray but found to be down-regulated with 454-sequencing. Blue spots: 32 genes being up-regulated in heart compared to skeletal muscle were identified with 454 but found to be down-regulated with cDNA microarray.