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Figure 6 | BMC Genomics

Figure 6

From: Systemic treatment of xenografts with vaccinia virus GLV-1h68 reveals the immunologic facet of oncolytic therapy

Figure 6

Mouse immune genes associated with the Immunologic Constant of Rejection Hypothesis. IPA self-organizing network based on genes with immune annotations whose expression was significantly up-regulated in VACV-infected GI-101A xenografts at day (A) 21 and (B) 42 from VACV-infection. (C) Self-organizing heat map based on genes associated with the ICR hypothesis. The genes were arbitrarily selected a priori based on previous studies as summarized in [2] and are displayed based on their expression in the current study without further selection.

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