Table 2 Number of genes over-expressed in xenografts excised from GLV-1h68 infected animals

VACV only

Permutation

House keeping (human/mouse)

Permutation

(cut off p²-value < 0.005 (unpaired Student t test)

(∑ 219)

test p-value

(∑ 337)

test p-value

GI-101A

7

0

N.S.

3

N.S.

GI-101A

21

219

< 0.001

(232)

< 0.001

GI-101A

42

216

< 0.001

(237)

< 0.001

HT-29

21

0

N.S.

(3)

N.S.

HT-29

42

0

N.S.

(10)

N.S.

All genes

Permutation

(cut off p²-value < 0.001 (unpaired Student t test)

(∑ 37 K)

test p-value

GI-101A

21

136

< 0.05

GI-101A

42

91

< 0.05

HT-29

21

4

N.S.

HT-29

42

10

N.S.

All genes

Permutation

(cut off p²-value < 0.001 (unpaired Student t test)

(∑ 37 K)

test p-value

GI-101A

21

105

< 0.05

GI-101A

42

1026

< 0.001

HT-29

21

7

N.S.

HT-29

42

14

N.S.