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Table 1 The list of the top-ranked 15 genes in each sub-module.

From: Exploring temporal transcription regulation structure of Aspergillus fumigatus in heat shock by state space model

Module

Gene

Heat shock at 37°C

Gene

Heat shock at 48°C

1(+)

AFU6G06470

Heatshock protein Hsp30-like, putative

AFU1G10130

Adenosylhomocysteinase

1(+)

AFU6G12160

C6 transcription factor, putative

AFU2G03610

IMP dehydrogenase, putative

1(+)

AFU7G05580

Phospholipase PldA, putative

AFU5G04220

Mitochondrial DNA replication protein

1(+)

AFU1G11220

hypothetical protein

AFU5G14660

GABA permease, putative

1(+)

AFU2G04020

Alpha, alpha-trehalose phosphate synthase subunit, putative

AFU4G07360

Cobalamin-independent methionine synthase MetH/D

1(+)

AFU6G00420

hypothetical protein

AFU7G01220

Farnesyl-diphosphate farnesyltransferase, putative

1(+)

AFU5G07340

DnaJ domain protein Psi, putative

AFU5G14650

RING finger protein

1(+)

AFU1G17020

UDP-Glucose dehydroGenase

AFU3G13400

nucleolar protein nop5

1(+)

AFU3G14540

Heatshock protein Hsp30/Hsp42, putative

AFU6G09990

Importinbeta-4subunit, putative

1(+)

AFU5G13750

Calcium binding protein Caleosin, putative

AFU3G03290

hypothetical protein

1(+)

AFU1G15270

Heat shock protein Hsp98/Hsp104/ClpA, putative

AFU5G05710

Centromere/microtubule-binding protein cbf5

1(+)

AFU4G13630

hypothetical protein

AFU6G11890

Dynamin GTPase, putative

1(+)

AFU3G01440

conserved hypothetical protein

AFU1G15900

Importinbeta-2subunit, putative

1(+)

AFU6G00410

amino acid permease, putative

AFU8G03930

Hsp70 chaperone

1(+)

AFU1G17010

Glutathione S-transferase, putative

AFU1G05990

RibosomalproteinL16a

1(-)

AFU7G05460

Putative uncharacterized protein

AFU6G06470

Heat shock protein Hsp30 like, putative

1(-)

AFU2G03610

IMP dehydrogenase, putative

AFU1G11180

Heat shockprotein/chaperonin HSP78, putative

1(-)

AFU6G09990

Importin beta-4subunit, putative

AFU3G00960

conserved hypothetical protein

1(-)

AFU1G06190

Histone H4 arginine methyltransferase RmtA

AFU3G12630

related to CYTOCHROME B561

1(-)

AFU1G15620

ATP-dependent RNA helicase HelA

AFU6G10470

Zinc finGer protein ZPR1

1(-)

AFU5G05710

Centromere/microtubule-bindinGprotein cbf5

AFU2G03060

Cactin

1(-)

AFU7G03690

Protein pxr1

AFU6G12160

C6 transcription factor, putative

1(-)

AFU8G03930

Hsp70 chaperone

AFU2G10910

MFS alpha-glucoside transporter, putative

1(-)

AFU3G13400

nucleolar protein nop5

AFU5G04170

Heat shock protein 90

1(-)

AFU6G10320

WD repeat protein; possible nuclear pore complex associated

AFU3G14550

RNA polymeraseII transcription factor B subunit 5

1(-)

AFU3G09600

sik1 protein

AFU4G06220

conserved hypothetical protein

1(-)

AFU3G10800

Eukaryotic translation initiation factor 3 subunit CLU1/TIF31, putative

AFU2G00210

hypothetical protein

1(-)

AFU1G09770

La domain family

AFU1G15270

Heat shock protein Hsp 98/Hsp 104/ClpA, putative

1(-)

AFU7G02610

hypothetical protein

AFU4G11620

DNA replication complex GINS protein psf3

1(-)

AFU1G09200

Ribosome bioGenesis protein Erb1, putative

AFU4G08810

unnamed protein product

2(+)

AFU6G08760

Proline oxidase PrnD

AFU7G01000

Aldehyde dehydrogenase, putative

2(+)

AFU6G08750

Delta-1-pyrroline-5-carboxylate dehydrogenase PrnC

AFU6G11430

Aldehyde dehydrogenase AldA, putative

2(+)

AFU6G07720

Phosphoenolpyruvate carboxykinase AcuF

AFU5G08930

Isovaleryl-CoA dehydrogenase IvdA, putative

2(+)

AFU3G11790

Galactose-proton symport, putative

AFU6G03590

Methyl citrate synthase precursor

2(+)

AFU3G14590

Copper amine oxidase, putative

AFU4G12010

2-oxoacid dehydrogenases acyltransferase, putative

2(+)

AFU6G03730

2-methyl citrate dehydratase, putative

AFU6G03060

MFS monosaccharide transporter, putative

2(+)

AFU6G02860

Isocitratelyase

AFU6G03730

2-methylcitrate dehydratase, putative

2(+)

AFU4G11310

Fructose-1,6-bisphosphatase Fbp1, putative

AFU6G02860

Isocitrate lyase

2(+)

AFU7G01000

Aldehyde dehydrogenase, putative

AFU3G01450

3-methyl-2-oxobutanoate dehydrogenase, putative

2(+)

AFU6G14200

Acetyl-CoA-acetyltransferase, putative

AFU6G06470

Heatshock protein Hsp30 like, putative

2(+)

AFU1G00410

cutinase transcription factor 1 beta

AFU3G09690

thaumatin-like protein, putative

2(+)

AFU2G00210

hypothetical protein

AFU3G00960

conserved hypothetical protein

2(+)

AFU4G12010

2-oxoacid dehydrogenases acyltransferase, putative

AFU5G04170

Heatshock protein 90

2(+)

AFU8G04130

C6 transcription factor

AFU6G08760

Prolineoxidase PrnD

2(+)

AFU4G08170

Succinate-semialde hydedehydrogenase Uga2, putative

AFU2G02050

Peptidyl-prolylcis-transisomerase D

2(-)

AFU6G10650

ATP citrate lyase, subunit1, putative

AFU4G06890

14-alphasterol demethylase Cyp51A

2(-)

AFU6G10660

ATP citrate lyase subunit

AFU1G14930

hypothetical protein

2(-)

AFU1G03150

C-14 sterol reductase

AFU7G05060

MGtC/SapB family membrane protein

2(-)

AFU1G17630

FAD/FMN-containing protein

AFU2G00320

Sterol delta5,6-desaturase, putative

2(-)

AFU5G02330

Ribonuclease mitogillin precursor

AFU3G14920

TAM domain methyltransferase, putative

2(-)

AFU4G11720

Phosphatidyl synthase

AFU1G03150

C-14 sterol reductase

2(-)

AFU3G08580

Glycine-rich RNA-binding protein, putative

AFU8G05990

hypothetical protein

2(-)

AFU2G00320

Sterol delta5,6-desaturase, putative

AFU4G14250

hypothetical protein

2(-)

AFU3G07230

Phosphopantothenate-cysteine ligase, putative

AFU5G02330

Ribonuclease mitogillin precursor

2(-)

AFU3G03580

Transferase family protein

AFU7G05490

hypothetical protein

2(-)

AFU3G10750

Acetate kinase, putative

AFU5G13730

invasion associated protein p60

2(-)

AFU6G07900

Rod1 protein

AFU5G06240

Alcohol dehydrogenase, putative

2(-)

AFU4G06890

14-alpha sterol demethylase Cyp51A

AFU1G16190

Probable glycosidase crf1 precursor

2(-)

AFU3G08990

unnamed protein product

AFU5G03800

High-affinity ironpermease

2(-)

AFU7G04730

major facilitator protein homolog, putative

AFU7G05500

Glutathione S-transferase, putative

  1. The heat shock proteins with similar expression pattern are assigned to same module. The average expression profiles of all heat response genes are shown at additional file 2.