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Table 4 Estimation of QTL for resistance traits to coccidiosis after inoculation with E. tenella in an F2 cross.

From: Microsatellite mapping of QTLs affecting resistance to coccidiosis (Eimeria tenella) in a Fayoumi × White Leghorn cross

QTL region1

Flanking markers

Trait2

Location (cM)

F

Additive effect ± se

Dominance effect ± se

Corrected Additive effect ± se

Corrected Dominance effect ± se

Reduction of σ2 (%)

Chrom-Wide Proba

Genome-Wide Proba

1-A

SEQALL0480-SEQALL0478

WG

216

8.79

-8.34 ± 2.44

8.29 ± 4.09

-3.20 ± 0.93

3.18 ± 1.57

6.5

0.005

0.024**

  

PC

216

6.88

-0.188 ± 0.056

0.109 ± 0.092

  

5.1

0.014

0.066*

  

HEMA

215

11.44

-1.788 ± 0.528

ns

  

4.3

0.009

0.043**

1-B

MCW0101-LEI0101

WG

254

17.42

-9.57 ± 2.29

ns

-3.67 ± 0.88

ns

6.4

0.0003

0.001***

  

PC

254

10.90

-0.173 ± 0.052

ns

  

4.1

0.0039

0.019**

2-A

MCW0173-ADL0267

248

11.15

0.146 ± 0.044

ns

  

4.2

0.016

0.10*

2-B

ADL0236-MCW0185

WG

297

6.78

-7.41 ± 2.52

7.05 ± 3.92

-2.84 ± 0.97

2.70 ± 1.50

5.1

0.024

0.15ns

3-A

LEI0161-MCW0212

143

8.21

-0.138 ± 0.048

ns

  

3.1

0.045

0.31ns

3-C

GCT053-MCW0040

WG

281

5.92

-7.42 ± 2.23

3.74 ± 3.55

-2.84 ± 0.85

1.43 ± 1.36

4.5

0.042

0.30ns

  

PC

281

7.86

-0.143 ± 0.051

   

3.9

0.050

ns

6-A

MCW0250-SEQALL0472

HEMA

59

10.61

-1.622 ± 0.498

ns

  

4.0

0.0062

0.19ns

  

PC

66

15.55

-0.207 ± 0.052

ns

  

5.7

0.0011

0.038**

6-B

SEQALL0472-SEQALL0486

WG

79

5.56

-7.78 ± 2.42

-4.88 ± 3.71

-2.98 ± 0.93

-1.87 ± 1.42

4.2

0.030

0.65ns

15

MCW0211-MCW0323

WG

50

6.7

6.56 ± 2.53

ns

-3.20 ± 0.93

ns

2.5

0.044

ns

  

HEMA

50

9.54

1.728 ± 0.559

ns

  

3.6

0.010

ns

  

LES

50

7.66

-0.248 ± 0.090

ns

  

2.9

0.025

ns

23-A

MCW0165-ADL0289

2

3.94

0.109 ± 0.047

-0.128 ± 0.073

  

3.0

0.050

ns

23-B

ADL0289-LEI0090

WG

8

5.5

5.87 ± 2.50

ns

2.25 ± 0.96

ns

2.1

0.044

ns

  1. 1QTL region = Chromosome number and letter to define sub-region; 2WG = 100 × (Body Weight (8 d post inoculation) – Body Weight (2 d before inoculation))/Body Weight (2 d before inoculation) (%); PC = Plasma Coloration 4 d post inoculation (log10(Optical Density at 480 nm)); T° = Rectal Body Temperature (°C) 4 d post inoculation; HEMA = Hematocrit Level (%) 4 d post inoculation; LES = Lesion (from 0 "no lesion" to 4 "most severe lesion") 7 d post inoculation;
  2. Genome-wide probabilities thresholds are indicated as very significant*** (P = 0.001), significant** (P < 0.05), suggestive* (P < 0.10) or non significant ns (P > 0.10).
  3. QTL with additive and dominance effects.