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Table 1 Genes down-regulated in the total RNA fraction in the presence of HTLV-I p30

From: Genome wide analysis of human genes transcriptionally and post-transcriptionally regulated by the HTLV-I protein p30

Probe ID

Gene Description

Gene

Fold Change

 

Transcription/Translation/RNA Processing

  

1554468_s_at

Mitochondrial Ribosomal Protein L38

FBF1

0.11

217340_at

Ribosomal Protein L21

RPL21

0.16

231658_x_at

Similar to Ribosomal Protein L36

LOC127295

0.19

243560_at

Heat Shock Transcription Factor 1

HSF1

0.24

216282_x_at

Polymerase (RNA) II (DNA Directed) Polypeptide C, 33 kda

POLR2C

0.25

236522_at

Nuclear Factor I/A

NFIA

0.27

1553181_at

DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 31

DDX31

0.27

216117_at

Exosome Component 2

EXOSC2

0.32

208345_s_at

Pou Domain, Class 3, Transcription Factor 1

POU3F1

0.37

1552499_a_at

Zinc Finger Protein 31 (Kox 29)

ZSCAN20

0.38

 

Metabolism

  

1569631_at

Nicotinamide Nucleotide Adenylyltransferase 1

NMNAT1

0.05

217203_at

Glutamate-Ammonia Ligase (Glutamine Synthetase)

GLUL

0.09

226209_at

NADH Dehydrogenase (Ubiquinone) Flavoprotein 3, 10 kda

NDUFV3

0.16

239333_x_at

Glutathione S-Transferase Subunit 13 Homolog

GSTK1

0.31

226947_at

Glucuronidase, Beta-Like 2

GUSBL2

0.34

213935_at

Abhydrolase Domain Containing 5

ABHD5

0.35

238724_at

2,3-Bisphosphoglycerate Mutase

BPGM

0.37

213582_at

ATPase, Class VI, Type 11a

ATP11A

0.38

236018_at

Adenosine Deaminase-Like

ADAL

0.40

 

Signal Transduction

  

1555340_x_at

Rap1a, Member Of Ras Oncogene Family

RAP1A

0.00

218711_s_at

Serum Deprivation Response (Phosphatidylserine Binding Protein)

SDPR

0.05

210374_x_at

Prostaglandin E Receptor 3 (Subtype Ep3)

PTGER3

0.12

216979_at

Nuclear Receptor Subfamily 4, Group A, Member 3

NR4A3

0.13

242875_at

Presenilin 1 (Alzheimer Disease 3)

PSEN1

0.13

204936_at

Mitogen-Activated Protein Kinase Kinase Kinase Kinase 2

MAP4K2

0.25

211471_s_at

Rab36, Member Ras Oncogene Family

RAB36

0.28

215134_at

Phosphatidylinositol 4-Kinase Type Ii

PI4K2A

0.33

219738_s_at

Protocadherin 9

PCDH9

0.35

239202_at

Rab3b, Member Ras Oncogene Family

RAB3B

0.36

205280_at

Glycine Receptor, Beta

GLRB

0.37

209101_at

Connective Tissue Growth Factor

CTGF

0.37

 

Cell Division/Cell Cycle

  

227578_at

Thymopoietin

TMPO

0.15

219831_at

Cyclin-Dependent Kinase-Like 3

CDKL3

0.29

 

Cytoskeleton

  

239067_s_at

Pannexin 2

PANX2

0.16

206117_at

Tropomyosin 1 (Alpha)

TPM1

0.31

205328_at

Claudin 10

CLDN10

0.33

 

Transport

  

216504_s_at

Solute Carrier Family 39 (Zinc Transporter), Member 8

SLC39A8

0.11

242554_at

Two Pore Segment Channel 2

TPCN2

0.40

 

Apoptosis

  

202730_s_at

Programmed Cell Death 4 (Neoplastic Transformation Inhibitor)

PDCD4

0.34

211603_s_at

Ets Variant Gene 4 (E1A Enhancer Binding Protein, E1af)

ETV4

0.34

244035_at

B-Cell Cll/Lymphoma 2

BCL2

0.36

 

Ubiquitin

  

241900_at

Smad Specific E3 Ubiquitin Protein Ligase 2

SMURF2

0.20

243216_x_at

Ubiquitin Specific Peptidase 40

USP40

0.38

 

Other/Unknown

  

233351_at

DNAI (Hsp40) Homolog, Subfamily C, Member 3

DNAJC3

0.08

243221_at

Family With Sequence Similarity 20, Member A

FAM20A

0.08

236378_at

Calcium And Integrin Binding Family Member 4

CIB4

0.09

222109_at

Guanine Nucleotide Binding Protein-Like 3 (Nucleolar)-Like

GNL3L

0.09

243989_at

Ku-Mel-3 Protein

KU-MEL-3

0.13

221225_at

Dephospho-Coa Kinase Domain Containing

DCAKD

0.13

229678_at

Male-Enhanced Antigen 1

MEA1

0.15

1552430_at

WD Repeat Domain 17

WDR17

0.24

211113_s_at

ATP-Binding Cassette, Sub-Family G (White), Member 1

ABCG1

0.28

207408_at

Solute Carrier Family 22 (Organic Cation Transporter), Member 14

SLC22A14

0.30

233532_x_at

Intraflagellar Transport 52 Homolog (Chlamydomonas)

IFT52

0.34

214181_x_at

Leukocyte-Specific Transcript 1

LST1

0.35

203404_at

Armadillo Repeat Containing, X-Linked 2

ARMCX2

0.36

203765_at

Grancalcin, Ef-Hand Calcium Binding Protein

GCA

0.36

1555046_at

FSH Primary Response (Lrpr1 Homolog, Rat) 1

CENPI

0.37

235991_at

CUB Domain Containing Protein 2

CDCP2

0.37

1554112_a_at

Unc-51-Like Kinase 2 (C. Elegans)

ULK2

0.37

235349_at

Family With Sequence Similarity 82, Member A

FAM82A

0.38

206928_at

Zinc Finger Protein 124 (Hzf-16)

ZNF124

0.39

236943_at

Lymphocyte Antigen 86

LY86

0.39

242996_at

Mitochondrial Translational Release Factor 1

MTRF1

0.40