Histogram of processed OCT4 ratios. a) Histogram of quality controlled and normalized OCT4 ChIP-on-chip ratios for the individual probes. The blue line represents the threshold for the upper 0.001 quantile of the distribution (green line: upper 0.01 quantile and red line upper 0.05 quantile, respectively). b) Histogram of distances between OCT4 binding sites and closest TSS for all 308 validated OCT4 target genes, (c) Histogram of distances between OCT4 binding sites and closest TSS for the 33 isolated functional OCT4 target genes. The red fraction corresponds to stemness related genes, the green fraction to differentiation related genes.