Figure 2

Multi-way glioma data set: MFA consensus between CGH and expression highlights a partition of gliomas into WHO classification. Individuals (tumors) are presented as points on the scatter plot created with the first two main dimensions of MFA. Each individual is colored following the glioma subtype (WHO classification); mean individual are also displayed. Projection of the tumors onto PC1 underlines a partition into glioblastomas (GBM) and lower grade gliomas (oligodendrogliomas, astrocytomas, oligoastrocytomas). PC2 mainly stresses differences between astrocytomas (A) and oligodendrogliomas (O). As PC1 and PC2 represents the first two main factors of MFA they could be interpretated: PC1 summarizes characteristics of glioblastoma i.e. transcriptional differences existing between glioblastomas and lower grade gliomas; PC2 summarizes characteristics of oligodendrogliomas as it stresses the differences between glial tumors coming from astrocytic cells from those arising from oligodendroglial ones.