Figure 3

Multi-way glioma data set: Characteristics of glioblastoma are linked to CGH and expression data whereas characteristics of oligodendrogliomas are mostly related to CGH data. The partial representation of the mean individuals (CGH and eX) for each WHO tumor type (A) and the group representation (B) are displayed. (A) The balanced representation of each category is located in the exact barycenter of the points summarizing partial points of view (CGH; linked by plain line and eX; linked by dot line). The projection of the partial representations for each category (CGH and eX for oligodendrogliomas, astrocytomas, oligoastrocytomas and glioblastomas) onto PC1 are very close; the partition of the tumors into WHO classification is thus shared by the genome and the transcriptome. On PC2, all the mean individuals from the partial expression representation (eX) are located around the origin. It is not the case for the genomic one (CGH). PC2 is therefore specific to the genomic point of view and is not shared by the expressional one. This is confirmed by analyzing the group representation (B): projection of the CGH and eX groups are closed along PC1 but only the one of CGH have a value close to 1 on PC2.