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Figure 6 | BMC Genomics

Figure 6

From: Simultaneous analysis of distinct Omics data sets with integration of biological knowledge: Multiple Factor Analysis approach

Figure 6

Single glioma data set: MFA highlights a good separation between glioblastomas and lower grade gliomas. Tumors are presented as points on the scatter plot created with the first two main dimensions of MFA. Each sample (dot) is colored following the glioma subtype (WHO classification); mean individual are also displayed (squares). Projection of the tumors onto PC1 underlines a separation between glioblastomas (GBM) and lower grade gliomas (oligodendrogliomas, astrocytomas, oligoastrocytomas). PC2 differentiates oligo-astrocytomas (OA) from the other subtypes (oligodendrogliomas, astrocytomas, GBM). PC1 is linked to characteristics of glioblastoma stating transcriptional differences between grade IV and lower grade gliomas. PC2 is related to characteristics of oligodendrogliomas highlighting OA particular signatures.

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BMC Genomics

ISSN: 1471-2164

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