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Table 3 Gene expression in different environments.

From: Natural variation in gene expression in the early development of dauer larvae of Caenorhabditis elegans

Gene

LG

Start (bp)

Gene

N2 vs DR1350

RIL-14 vs RIL-17

    

T

L

T × L

DI

T

L

DI

mppa-1

I

1740648

Mitochondrial processing peptidase alpha

*

  

↓

**

 

↓

Y54E10A.16

I

3246074

-

    

**

 

↑

F27C1.10

I

5433925

-

**

**

**

↑

   

T09B4.8

I

6164721

Alanine-glyoxylate aminotransferase*

    

**

 

↓

sdha-2

I

10683275

Succinate dehydrogenase complex, subunit A

    

**

 

↓

prx-11

I

12971603

Peroxisome assembly factor

**

**

 

↑

   

W04A8.4

I

13841882

-

 

**

  

**

**

↑

C50D2.5

II

98402

-

    

**

 

↓

Y110A2AL.4

II

2839303

-

*

**

**

DR↓

   

F12E12.11

II

3742459

-

**

**

 

↑

   

acdh-2

II

5547461

Acyl coA dehydrogenase

    

**

 

↑

sra-29

II

6574325

Serpentine receptor, class A

    

**

 

↓

icd-1

II

6587524

Inhibitor of cell death (RNA polymerase II general transcription factor*)

 

**

  

**

 

↓

T02G5.2

II

7095427

-

**

**

 

↑

   

DH11.2

II

8012740

-

**

**

 

↑

   

pyr-1

II

8651059

Pyrimidine biosynthesis

*

  

↓

**

 

↓

C01G6.7

II

9291932

acs-7 (fatty acid coA syhthetase family)

*

**

 

↑

**

 

↑

cyp-13A5

II

9798193

Cytochrome P450 family

    

**

 

↑

C05C10.4

II

9931760

pho-11 (intestinal acid phosphatase)

*

**

 

↓

**

 

↓

B0334.3

II

11489513

Thiamine pyrophosphate-requiring enzyme*

    

**

 

↑

F01D5.1

II

13996851

Secreted surface protein*

    

**

 

↓

F58B6.1

III

1112319

-

*

**

**

DR↓

*

 

↓

Y54H5A.1

III

5153423

Ribosome assembly protein*

 

**

  

**

 

↓

dhs-9

III

5364479

Dehydrogenase, short chain

**

  

↑

*

 

↑

dlc-1

III

6462849

Dynein light chain

 

**

  

**

 

↓

F44B9.2

III

8022392

-

    

**

 

↓

eif-3.D

III

8969556

Eukaryotic initiation factor

    

**

 

↓

iff-1

III

9745765

Initiation factor homologue

*

  

↓

**

 

↓

ran-1

III

10746465

Ran GTPase orthologue

 

**

  

**

 

↓

T28D6.6

III

11326536

GTP-binding protein DRG1

    

**

 

↓

Y111B2A.2

III

12495966

-

*

  

↓

**

 

↓

Y37D8A.18

III

12926440

Mitochondrial ribosomal protein S10*

 

**

  

**

 

↓

abce-1

III

13153697

ABC transporter class E

**

**

 

↓

**

**

↓

tag-61

III

13463042

ant-1.1 (adenine nucleotide translocator)

    

**

 

↑

K02D7.1

IV

292425

Purine nucleoside phosphorylase*

*

**

 

↑

**

 

↑

C18H7.1

IV

615544

von Willebrand factor and related coagulation proteins*

    

**

 

↑

K03H6.2

IV

1510563

-

*

**

**

N2↑

   

C17H12.4

IV

6798908

Carboxylesterase and related proteins*

*

 

**

↑

**

 

↑

D2096.8

IV

8377687

Nucleosome assembly protein*

 

**

  

**

 

↓

T20D3.3

IV

9333319

-

 

**

  

**

 

↓

C08F8.2

IV

11149161

Mitochondrial RNA helicase SUV3*

 

**

  

**

 

↓

kin-4

IV

11436618

Protein kinase

    

**

 

↓

F08G5.6

IV

12435797

-

**

  

↓

**

**

↓

clec-186

IV

12866085

C-type lectin

**

 

**

↓

*

 

↓

F55G11.2

IV

12967418

-

**

**

 

↓

*

 

↓

F49E11.11

IV

13059587

scl-3 (SCP-like extracellular protein)

**

  

↓

**

 

↓

C39E9.4

IV

13068737

scl-6 (SCP-like extracellular protein)

*

  

↓

**

 

↓

ugt-22

IV

13639234

UDP-glucuronosyl transferase

**

  

↓

**

 

↓

Y43D4A.2

IV

16744614

-

**

**

 

↓

*

 

↓

ZK550.6

IV

17260269

Peroxisomal phytanoyl-CoA hydroxylase*

**

**

 

↑

**

 

↑

C49C3.7

IV

17332528

-

    

**

 

↑

dod-19

V

411783

Downstream of DAF-16

*

  

↓

**

 

↓

C14C6.5

V

536629

-

**

  

↓

   

W07B8.4

V

1130090

Cysteine proteinase Cathepsin L*

**

 

**

↑

*

 

↑

Y19D10A.9

V

2351676

clec-29 (C-type lectin)

**

**

 

↓

**

 

↓

F56A4.10

V

2461320

Permease of the major facilitator superfamily*

**

**

 

↓

**

 

↓

cyp-35A5

V

3936359

Cytochrome P450 family

*

  

↓

**

 

↓

T22F3.11

V

3612160

Permease of the major facilitator superfamily*

**

  

↑

**

 

↑

F13H6.4

V

6366416

Carboxylesterase and related proteins*

**

  

↓

   

ugt-41

V

7161049

UDP-glucuronosyl transferase

*

  

↓

**

 

↓

cyp-35A2

V

7362298

Cytochrome P450 family

**

  

↓

*

**

↓

srx-3

V

9005518

Serpentine receptor, class X

*

**

**

N2↓

   

dhs-18

V

11045678

Dehydrogenase, short chain

**

**

 

↑

*

 

↑

snf-11

V

11305047

Sodium neurotransmitter symporter family

    

**

 

↓

F35B12.4

V

11609217

Serine proteinase inhibitor*

 

**

  

**

 

↓

F45D3.4

V

12552186

-

 

**

  

**

 

↑

ugt-16

V

12825004

UDP-glucuronosyl transferase

*

  

↓

**

 

↓

T16G1.4

V

12940017

Small molecule kinase*

*

  

↑

**

 

↑

F35E12.5

V

13737072

-

**

  

↓

**

 

↓

cyp-35C1

V

13898467

Cytochrome P450 family

**

  

↓

**

 

↓

ret-1

V

14829155

Reticulon protein

    

**

 

↓

cdr-1

V

15921335

Cadmium responsive

*

  

↓

**

 

↓

nhr-127

V

16262268

Nuclear hormone receptor family

**

**

 

↑

*

 

↑

T26H2.5

V

19230746

-

**

  

↑

*

 

↑

daf-28

V

19810833

Beta-type insulin

*

**

 

↓

**

**

↓

K02E2.7

V

20380157

-

    

**

**

↑

B0310.3

X

510900

-

    

**

 

↑

T10H10.2

X

2294743

FAD-dependent sulfhydryl oxidase/quiescin and related proteins*

 

**

  

**

**

↑

tag-18

X

3731903

-

*

**

 

↓

**

**

↓

amt-1

X

4571419

Ammonium transporter homologue

*

**

**

N2↑

   

F13D11.3

X

5804348

-

**

**

 

↑

   

nnt-1

X

6122273

Nicotinamide nucleotide transhydrogenase

*

  

↑

**

 

↑

C46F2.1

X

8077686

-

    

**

 

↓

D2021.8

X

8552200

-

**

**

**

↓

   

C35C5.8

X

11533977

-

*

  

↑

**

 

↑

cah-4

X

13542493

Carbonic anhydrase

*

  

↑

**

 

↑

F23D12.3

X

14442540

-

**

**

 

↓

   

egrh-1

X

14845856

Early growth factor response factor homologue

    

**

 

↑

F09B12.3

X

15095252

-

*

  

↑

**

 

↑

  1. The 89 genes, their linkage group (LG) and location (Start), whose expression is significantly affected by TREATMENT (T), or TREATMENT × LINE (T × L) at p < 0.001 (**) and under dauer larva-inducing (DI) conditions up (↑) or down (→) regulation, and this specified for N2 or DR1350 specific TREATMENT × LINE effects. For these genes (above) other significant TREATMENT (p < 0.05 and p < 0.001) and LINE (L) (p < 0.001) only effects are also reported, with p < 0.05 and p < 0.001 shown by * and **, respectively. Gene is the WormBase gene identification [41], with NCBI KOGs shown by *.