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Figure 2 | BMC Genomics

Figure 2

From: Signed weighted gene co-expression network analysis of transcriptional regulation in murine embryonic stem cells

Figure 2

Unsigned and Signed Mouse ES cell Networks in Ivanova et al. a, left, Dendrogram of the unsigned network of the Ivanova et al (2006) data set with color bands below indicating module membership for the unsigned network (U) and the signed network (S). a, right, heat map for visualizing standardized gene expressions (rows) across samples (columns) for genes in the turquoise module in the unsigned network. b, left, Dendrogram of the signed network of the Ivanova et al (2006) data set with color bands below indicating module membership for the signed network (S) and the unsigned network (U). b, right, heat map of expression profiles across samples for genes in the turquoise, black, and blue modules in the signed network. Note, modules are not scaled to reflect the number of genes in each module. c, scatter plot of module membership, k ME , (x-axis) plotted against gene significance, GS, (y-axis) for the black and blue modules in the signed network with known ES cell regulators and differentiation genes labelled.

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