Expression Changes Versus Module Membership in the Black and Blue Modules (Zhou et al). Module membership, k
, is plotted against log2 expression fold change (FC) for the black (a) and blue (b) modules in the unsigned network of the Zhou et al (2007) data. FC is the ratio between the average expression in Oct4 positive samples and Oct4 negative microarray samples. Known ES cell regulators are labeled. Genes are colored by module membership in the signed network. c and d are analogous to a and b but module membership is with regard to the signed black and blue modules.