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Table 3 Transcription Factor Binding in Zhou et al Networks

From: Signed weighted gene co-expression network analysis of transcriptional regulation in murine embryonic stem cells

Unsigned Network

Module

No. of genes

Oct4Complex

cMycComplex

Suz12

black

2659

1.55, 2.08e-09

1.4, 4.18e-46

0.666, 6.21e-10

blue

1484

0.872, 0.172

1.09, 0.0125

1.01, 0.447

brown

992

1.2, 0.093

1.02, 0.315

1.11, 0.127

green

1493

0.758, 0.028

0.863, 0.000186

1.36, 4.79e-06

grey

7318

0.766, 1.87e-08

0.803, 1.69e-51

1.2, 7.19e-14

magenta

1583

0.919, 0.28

1.04, 0.147

1.1, 0.0982

red

2593

1.48, 2.3e-07

1.64, 4.02e-107

0.437, 2.49e-26

turquoise

838

0.997, 0.459

1.3, 1.74e-08

0.829, 0.0631

yellow

2002

1.08, 0.213

1.1, 0.00171

0.844, 0.0106

Signed Network

black

1859

1.94, 2.94e-15

1.4, 4.22e-30

0.523, 2.19e-13

blue

1972

0.656, 0.000465

1.03, 0.18

1.13, 0.03

brown

1267

1.45, 0.000755

1.72, 1.22e-59

0.411, 5.78e-14

green

1548

0.818, 0.0763

0.933, 0.0414

1.27, 0.000329

grey

7175

0.729, 1.64e-10

0.784, 2.34e-59

1.24, 2.7e-18

pink

659

0.941, 0.432

1.27, 5e-06

0.474, 2.48e-06

red

2184

1.48, 2.18e-06

1.63, 1.7e-85

0.493, 9.37e-18

turquoise

2317

0.896, 0.156

1.05, 0.0498

1.09, 0.0716

yellow

1870

1.17, 0.0587

1.05, 0.0545

0.885, 0.054

  1. Module enrichments for binding by the Oct4 and cMyc TF Groups amd Suz12. Each enrichment score (before the comma) is followed by its corresponding p-value calculated from the hyper-geometric distribution (uncorrected for multiple comparisons).
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BMC Genomics

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