Table 4 RpoS-dependent EDL933-specific O-island genes (MER ≥ 2, P < 0.05). These are not present in E. coli K12 MG1655. MER: mean expression ratio (WT/rpoS).
From: Global effect of RpoS on gene expression in pathogenic Escherichia coli O157:H7 strain EDL933
Gene | Expression (log2) | MER | Position | Function | |
|---|---|---|---|---|---|
| Â | WT | rpoS | Â | Â | Â |
Z0321 | 12.4 ± 0.0 | 10.0 ± 0.3 | 6 | O-Island 8 | Putative regulator (prophage CP-933H) |
Z0443 | 10.0 ± 0.1 | 6.7 ± 0.1 | 10 | O-Island 19 | Unknown |
Z0463 | 7.2 ± 0.8 | 2.2 ± 0.0 | 32 | O-Island 20 | Putative response regulator |
Z0608 | 10.8 ± 0.4 | 5.0 ± 1.0 | 55 | O-Island 28 | Putative outer membrane export protein |
Z0609 | 6.5 ± 0.6 | 2.2 ± 0.0 | 20 | O-Island 28 | Unknown |
Z0701 | 5.6 ± 0.3 | 3.7 ± 0.3 | 4 | O-Island 30 | Unknown |
Z0702 | 10.4 ± 0.2 | 9.2 ± 0.1 | 2 | O-Island 30 | Unknown (Rhs Element Associated) |
Z0957 | 12.0 ± 0.1 | 10.6 ± 0.2 | 3 | O-Island 36 | Unknown (prophage CP-933K) |
Z0958 | 11.8 ± 0.4 | 10.0 ± 0.1 | 3 | O-Island 36 | Unknown (prophage CP-933K) |
Z0984 | 5.7 ± 0.2 | 4.2 ± 0.2 | 3 | O-Island 36 | Unknown (prophage CP-933K) |
Z1129 | 9.1 ± 0.2 | 7.9 ± 0.3 | 2 | O-Island 43 | Putative enzyme |
Z1185 | 11.5 ± 0.2 | 10.3 ± 0.2 | 2 | O-Island 43 | Unknown |
Z1190 | 12.2 ± 0.7 | 7.9 ± 0.2 | 20 | O-Island 43 | Putative enzyme |
Z1193 | 10.2 ± 0.8 | 6.3 ± 0.8 | 15 | O-Island 43 | Unknown |
Z1385 | 11.8 ± 0.1 | 10.5 ± 0.3 | 2 | O-Island 44 | Unknown (cryptic prophage CP-933M) |
Z1386 | 7.1 ± 0.3 | 5.8 ± 0.2 | 2 | O-Island 44 | Unknown (cryptic prophage CP-933M) |
Z1528 | 6.5 ± 0.3 | 3.3 ± 0.7 | 9 | O-Island 47 | Unknown |
Z1629 | 12.2 ± 0.8 | 5.3 ± 0.3 | 117 | O-Island 48 | Putative enzyme |
Z1764 | 9.0 ± 0.2 | 7.3 ± 0.2 | 3 | O-Island 50 | Putative enzyme (prophage CP-933N) |
Z1922 | 9.9 ± 0.8 | 4.8 ± 0.2 | 35 | O-Island 52 | Unknown (prophage CP-933X) |
Z1923 | 8.9 ± 1.0 | 2.9 ± 0.1 | 64 | O-Island 52 | Unknown (prophage CP-933X) |
Z1924 | 11.1 ± 0.9 | 4.0 ± 0.2 | 137 | O-Island 52 | Unknown (prophage CP-933X) |
Z2048 | 4.1 ± 0.2 | 2.3 ± 0.1 | 3 | O-Island 57 | Unknown (prophage CP-933O) |
Z2057 | 5.9 ± 0.2 | 4.3 ± 0.4 | 3 | O-Island 57 | Putative enzyme (prophage CP-933O) |
Z2124 | 6.0 ± 0.2 | 5.0 ± 0.1 | 2 | O-Island 57 | Unknown (prophage CP-933O) |
Z2149 | 13.4 ± 0.4 | 10.1 ± 0.3 | 10 | O-Island 57 | Unknown (Phage or Prophage Related) |
Z2150 | 10.4 ± 0.6 | 5.3 ± 0.4 | 33 | O-Island 57 | Unknown (Phage or Prophage Related) |
Z2151 | 11.6 ± 0.4 | 8.6 ± 0.1 | 8 | O-Island 57 | Unknown (Phage or Prophage Related) |
Z2164 | 6.8 ± 0.1 | 4.3 ± 0.6 | 6 | O-Island 59 | Putative regulator |
Z2254 | 6.9 ± 0.2 | 4.7 ± 0.6 | 5 | O-Island 64 | Unknown (Rhs Element Associated) |
Z2994 | 8.9 ± 0.2 | 6.8 ± 0.1 | 4 | O-Island 76 | Unknown (prophage CP-933T) |
Z3391 | 9.9 ± 0.5 | 7.1 ± 0.4 | 7 | O-Island 95 | Putative enzyme |
Z3392 | 8.4 ± 0.4 | 5.0 ± 0.2 | 11 | O-Island 95 | Putative enzyme |
Z3393 | 7.4 ± 0.3 | 2.2 ± 0.0 | 36 | O-Island 95 | Putative enzyme |
Z3394 | 6.0 ± 0.1 | 2.3 ± 0.0 | 13 | O-Island 95 | Putative transporter |
Z3623 | 9.4 ± 0.3 | 4.8 ± 0.1 | 24 | O-Island 102 | Sucrose permease |
Z3624 | 8.5 ± 0.2 | 2.5 ± 0.0 | 64 | O-Island 102 | D-fructokinase |
Z3625 | 9.4 ± 0.1 | 2.2 ± 0.0 | 139 | O-Island 102 | Sucrose hydrolase |
Z3947 | 8.3 ± 0.4 | 4.0 ± 0.5 | 19 | O-Island 108 | Unknown (Phage or Prophage Related) |
Z4488 | 7.8 ± 0.2 | 5.6 ± 0.4 | 4 | O-Island 126 | Putative enzyme |
Z4803 | 6.4 ± 0.9 | 2.4 ± 0.1 | 17 | O-Island 134 | Putative enzyme |
Z5114 | 7.4 ± 0.3 | 4.9 ± 0.4 | 6 | O-Island 148 | LEE-encoded virulence protein CesF |
Z5139 | 14.0 ± 0.4 | 12.0 ± 0.5 | 4 | O-Island 148 | LEE-encoded virulence protein |
Z5140 | 14.2 ± 0.3 | 12.6 ± 0.3 | 3 | O-Island 148 | LEE-encoded regulator Ler |
Z5199 | 9.7 ± 0.3 | 6.6 ± 0.5 | 8 | O-Island 152 | Unknown |
Z5200 | 9.0 ± 0.7 | 3.3 ± 0.2 | 53 | O-Island 152 | Unknown |
Z5619 | 7.3 ± 0.3 | 6.0 ± 0.3 | 3 | O-Island 166 | Putative regulator |
Z5684 | 7.3 ± 0.1 | 3.4 ± 0.5 | 15 | O-Island 167 | Putative regulator |
Z5887 | 8.3 ± 0.1 | 6.2 ± 0.3 | 4 | O-Island 172 | Unknown |
Z6024 | 9.3 ± 0.3 | 3.0 ± 0.1 | 78 | O-Island 71 | EspI, essential for virulence |