Figure 1

The genomic location of CNVs. (A) Frequencies of CNV for each gene along the genome for each chromosome is shown above the axis for amplifications and below the axis for deletions. Total numbers of CNV genes are given at the left hand side of each chromosome with the number of CNV var, rifin and stevor genes in brackets. (B) Distance to telomeric ends is shown to be significantly decreased in CNV genes (grey bars) in comparison to non-CNV genes (hashed bars). (C) Fraction of a chromosomal gene content classed as a CNV gene declined as number of genes per chromosome increased (open circles), this trend became weaker when the chromosomal portion excluding the sub-telomeric ends was examined (black closed circles). A significant divergence in gradient from 0 was detected only when all genes were analysed together, with multiple-adjusted r² values indicating a prominent role for chromosome length in predicting its proportion of CNV genes.