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Table 1 Properties of CNV genes compared with non-CNV genes in P. falciparum

From: Gene copy number variation throughout the Plasmodium falciparum genome

Property

 

Common CNVs

(n = 87)

Rare CNVs

(n = 99)

  

p-value

Observed

Expected

p-value

observed

expected

Proximity to centromeresb

↑

0.012

n/a

n/a

0.0001

n/a

n/a

Proximity to telomeresb

↑

<0.0001

n/a

n/a

<0.0001

n/a

n/a

Signal peptidea

n/a

0.92

14

13.8

0.59

18

13.1

Tm domaina

↑

0.027

35

25.24

0.0002

48

30.35

Length (bp)b

↓

<0.0001

n/a

n/a

<0.0001

n/a

n/a

Proximity to segmental duplications

↑

<0.0001

n/a

n/a

<0.0001

n/a

n/a

Rodent malaria parasite orthologuea

↓

<0.0001

13

64.38

<0.0001

32

77.42

P. knowlesi orthologuea

↓

<0.0001

15

64.5

<0.0001

37

77.56

any orthologuesa

↓

<0.0001

18

55.3

<0.0001

37

66.5

  1. Expected values were calculated under the assumption that each property is distributed evenly throughout the genome
  2. Values where p < 0.05 shaded in bold
  3. aChi-squared test; bKolmogorov-Smirnov test