Statistical aspects of discerning indel-type structural variation via DNA sequence alignment

BMC Genomics

Table 2 Representative insert types for discovery over the SV spectrum

insert type	λ (kb)	COV (%)	r (bp)
Illumina GA short^a	0.25	12	50
Illumina GA intermediate^b	3	12	50
454^c	3.2	25	250
Illumina GA long^d	10	12	50
fosmid^e	39.9	7	600
BAC^f	136.4	21	600

^arepresentative of < 1 kb inserts, see e.g. refs. [4, 29]
^binsert length representative of extended chemistry protocols for 2–5 kb inserts, see e.g. ref. [33]
^clibrary parameters reported in ref. [8]
^dexperimental, not currently in routine use
^elibrary parameters reported in ref. [6]
^fprimary breast tumor library B421, see ref. [11]

ISSN: 1471-2164