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Table 2 Inactivating mutations unique to either AKU_12601 or ATCC9150

From: Pseudogene accumulation in the evolutionary histories of Salmonella enterica serovars Paratyphi A and Typhi

Gene

Mutation

Strain

Gene product

aidB

del

AKU_12601

probable acyl Co-A dehydrogenase

asnB

1 bp del (homopol)

ATCC9150

asparagine synthetase B

ccmH

88 bp del

AKU_12601

cytochrome c-type biogenesis protein H2

gltJ

nonsense SNP

AKU_12601

glutamate/aspartate transport system permease

nmpC

IS10 ins

AKU_12601

outer membrane porin

pduF

1 bp del (homopol)

ATCC9150

propanediol diffusion facilitator

pduG

171 bp del

AKU_12601

propanediol dehydratase reactivation protein

proQ

7 bp del

ATCC9150

ProP effector

rbsC

1 bp ins (homopol)

ATCC9150

high affinity ribose transport protein

rbsR

1 bp ins (homopol)

ATCC9150

ribose operon repressor

rhlB

2 bp ins

ATCC9150

putative ATP-dependent RNA helicase

SSPA1447

nonsense SNP

AKU_12601

putative oxidoreductase

SSPA3202

1 bp ins (homopol)

AKU_12601

putative lipoprotein

SSPA3581

nonsense SNP

AKU_12601

conserved hypothetical protein

tesB

352 bp del

ATCC9150

acyl-CoA thioesterase II

trpD

nonsense SNP

AKU_12601

anthranilate synthase component II

wcaA

1 bp ins (homopol)

AKU_12601

putative glycosyl transferase

yaaJ

1 bp del

ATCC9150

putative amino-acid transport protein

yeaG

1 bp del

ATCC9150

conserved hypothetical protein

yeeO

1 bp ins (homopol)

ATCC9150

putative inner membrane protein

yhaO

nonsense SNP

ATCC9150

putative transport system protein

yjhW

nonsense SNP

ATCC9150

putative membrane protein

  1. Insertion, deletion or substitution events identified between Paratyphi A strains AKU_12601 and ATCC9150, causing gene inactivation in one strain. Strain – Paratyphi A strain in which the inactivating mutation occurs; del – deletion; ins – insertion; homopol – variation in homopolymeric sequence.