Confirmation and fine-mapping of a major QTL for resistance to infectious pancreatic necrosis in Atlantic salmon (Salmo salar): population-level associations between markers and trait

Table 1 Significant and suggestive QTL for resistance to IPN

Linkage group	Position (cM)	F	No of informative parents	Chromosome-wise p-value	Proportion of phenotypic variance
21	6	43.34†	19	≈ 0†	24.6%
4	9	2.44*	20	0.001	0.9%
13	18	2.37	18	0.003	0.9%
22	65	2.31	19	0.007	0.9%
10	27	2.26	19	0.008	0.8%
17a	1	2.25	18	0.004	0.8%
25	7	2.21	19	0.003	0.8%
2	49	2.08	20	0.010	0.7%
11	44	2.04	19	0.009	0.7%
3	31	2.02	20	0.005	0.7%
17b	14	2.00	17	0.018	0.6%
12	0	1.82	20	0.049	0.5%
28	1	1.79	19	0.047	0.5%
24	0	1.78	19	0.024	0.5%
16	0	1.61	20	0.045	0.4%

*P < 0.05 (genome-wide)
†P ≈ 0 (P-value too low to be determined by permutation testing)
QTL were defined as suggestive if they were chromosome-wise significant at P < 0.05, while not experiment-wise significant at P < 0.05. The F ratio has degrees of freedom equal to the number of informative parents and the number of records (offspring) minus two times the number of informative parents [38]; the latter ranging from 3177 to 3737 depending on the number of marker-informative offspring. The proportion of phenotypic variance is the proportion of phenotypic variance explained by the QTL, after correction for selective genotyping.

ISSN: 1471-2164