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Table 6 ChIP-Seq simulations of depth of sequencing for S. cerevisiae

From: Efficient yeast ChIP-Seq using multiplex short-read DNA sequencing

Fold Enrichment

2×

5×

10×

50×

Number of Reads

2,500,000

260,000

90,000

18,000

  1. Number of reads required in order to identify greater than 95% of 600 simulated binding sites distributed evenly over the 12 Mb S. cerevisiae genome with average fold enrichments of 2×, 5×, 10× and 50×. See Methods for details of the simulation.
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BMC Genomics

ISSN: 1471-2164

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