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Table 1 With or without the contribution of large gene family members, greater than 50% of the Trypanosoma cruzi genes detected on whole-genome, oligonucleotide microarrays were significantly stage-regulated at the RNA level.

From: The steady-state transcriptome of the four major life-cycle stages of Trypanosoma cruzi

  

# spots (percent of total)

# genes (percent of total)

all

SIG1

4273 (51.6)

6708 (52.2)

 

NON-SIG2

4000 (48.4)

6141 (47.8)

 

Total

8273 (100)

12849 (100)

large gene families3

SIG

739 (50.1)

1010 (51.5)

 

NON-SIG

735 (49.9)

950 (48.5)

 

Total

1474 (100)

1960 (100)

minus large gene families

SIG

3534 (52.0)

5698 (52.3)

 

NON-SIG

3265 (48.0)

5191 (47.7)

 

Total

6799 (100)

10889 (100)

  1. The oligonucleotide sequences were aligned against the T. cruzi genome by BLAST analysis [58]. Oligonucleotides showing 80% or greater identity with more than three T. cruzi gene ID's were not counted.
  2. 1Significantly stage-regulated as determined by SAM analysis (FDR = 0.4%).
  3. 2Non-significantly stage-regulated as determined by SAM analysis (FDR = 0.4%).
  4. 3Oligonucleotides mapping to members of large gene families (number of members > 30).
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BMC Genomics

ISSN: 1471-2164

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