Table 1 Upregulated genes identified in mantle and gill tissues 14 and 48 days after challenge with washed and unwashed QPX cells.

stress response and detoxification

4% of sequences identified in libraries from mantle tissue

11% of sequences identified in libraries from gill tissue

metallothionein

Corbicula fluminea

1e-11

Mantle (14 days)

GO915213

cytochrome P450 like TBP

Nicotiana tabacum

2e-07

Gills (14 days)

GO915227

71 kDa heat shock protein

Haliotis tuberculata

6e-53

Mantle (48 days)

GO915235

ferritin subunit

Meretrix meretrix

3e-50

Mantle (48 days)

GO915233

cell communication, immune system and membrane receptors

7% of sequences identified in libraries from mantle tissue

receptor of Activated Kinase C 1

Mya arenaria

4e-44

Mantle (48 days)

GO915258

lysozyme (Chain)

Enterobacteria phage T4

3e-04

Mantle (48 days)

GO915259

big defensin

Tachypleus tridentatus

5e-10

Mantle (48 days)

GO915266

sialic acid binding lectin

Helix pomatia

1e-04

Mantle (48 days)

GO915267

C-type lectin A

Chlamys farreri

5e-05

Mantle (14 days)

GO915219

nicotinic acetylcholine receptor subunit type H

Lymnaea stagnalis

8e-14

Mantle (14 days)

GO915224

cell cycle regulation, DNA repair, protein

4% of sequences identified in libraries from mantle tissue

regulation and transcription

26% of sequences identified in libraries from gill tissue

CCAAT/enhancer binding protein

Aplysia kurodai

5e-19

Mantle (14 days)

GO915218

translation elongation factor 1-alpha

Dreissena polymorpha

3e-108

Mantle (14 and 48 days) and Gills (48 days)

GO915211

elongation factor 1 beta

Plutella xylostella

4e-21

Mantle (48 days)

GO915246

eukaryotic translation elongation factor 1 delta

Bos taurus

4e-12

Mantle (48 days)

GO915241

similar to H3 histone, family 3B

Macaca mulatta

9e-37

Mantle (48 days)

GO915263

cytoskeleton production and maintenance

4% of sequences identified in libraries from mantle tissue

1% of sequences identified in libraries from gill tissue

Actin

Chlamys farreri

4e-67

Mantle (48 days)

GO915239

myosin (essential light chain)

Macrocallista nimbosa

3e-38

Mantle (48 days)

GO915247

Tropomyosin

Balanus rostratus

7e-15

Mantle (48 days)

GO915261

alpha tubulin

Leishmania braziliensis

2e-05

Mantle (48 days)

GO915252

beta-tubulin

Halocynthia roretzi

2e-59

Gills (14 days)

GO915225

transgelin 3

Danio rerio

1e-08

Mantle (48 days)

GO915232

respiratory chain

12% of sequences identified in libraries from mantle tissue

11% of sequences identified in libraries from gill tissue

cytochrome oxidase subunit 1

Ruditapes philippinarum

2e-29

Mantle and Gills (14 and 48 days)

GO915255

cytochrome oxidase subunit 3

Inocellia crassicornis

3e-19

Mantle (14 and 48 days)

GO915234

NADH dehydrogenase subunit 4

Ruditapes philippinarum

3e-30

Mantle and Gills (48 days)

GO915245

ATP synthase subunit 6

Ruditapes philippinarum

3e-25

Mantle and Gills (14 days)

GO915223

Metabolism

6% of sequences identified in libraries from gill tissue

zinc-dependent alcohol dehydrogenase

Lysiphlebus testaceipes

1e-33

Gills (14 days)

GO915228

ribosomal proteins

3% of sequences identified in libraries from mantle tissue

1% of sequences identified in libraries from gill tissue

ribosomal protein L17A

Argopecten irradians

8e-11

Mantle (48 days)

GO915262

ribosomal protein L11

Ictalurus punctatus

2e-08

Mantle (48 days)

GO915248

ribosomal protein S2e

Onchocerca volvulus

8e-25

Gills (48 days)

GO915270

ribosomal protein S3a

Crassostrea gigas

5e-99

Mantle (14 days)

GO915220

unknown functions

1% of sequences identified in libraries from mantle tissue

29% of sequences identified in libraries from gill tissue

putative senescence-associated protein

Pisum sativum

3e-34

Gills (14 days)

GO915231

hypothetical protein TTHERM_02141640

Tetrahymena thermophila SB210

2e-36

Gills (14 days)

GO915230

hypothetical protein TTHERM_00648850

Tetrahymena thermophila SB210

8e-09

Mantle (48 days)

GO915260

SJCHGC09076 protein

Schistosoma japonicum

4e-03

Mantle (48 days)

GO915249

unknown genes

16% of sequences identified in libraries from mantle tissue

11% of sequences identified in libraries from gill tissue

7 sequences

Mantle (14 days)

15 sequences

Mantle (48 days)

2 sequences

Gills (14 days)

4 sequences

Gills (48 days)