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Table 2 Downregulated genes identified in mantle and gill tissues 14 and 48 days after challenge with washed and unwashed QPX cells.

From: Identification and expression of differentially expressed genes in the hard clam, Mercenaria mercenaria, in response to quahog parasite unknown (QPX)

Homolog proteins

Homolog species

BlastX value

Libraries

GenBank accession no

stress response and detoxification

8% of sequences identified in libraries from mantle tissue

HSP70

Mytilus galloprovincialis

1e-52

Mantle (14 days)

GO915169

71 kDa heat shock protein

Haliotis tuberculata

6e-53

Mantle (14 days)

GO915166

cell communication, immune system and membrane receptors

5% of sequences identified in libraries from mantle tissue

hemocyte defensin

Crassostrea gigas

1e-05

Mantle (48 days)

GO915199

peroxisome proliferator-activated receptor

Oncorhynchus keta

7e-07

Mantle (14 and 48 days)

GO915177

thioester-containing protein

Euphaedusa tau

2e-08

Mantle (48 days)

GO915190

cell cycle regulation, DNA repair, protein regulation and transcription

3% of sequences identified in libraries from mantle tissue

transcription factor AP-1

Strongylocentrotus purpuratus

2e-16

Mantle (48 days)

GO915178

translation elongation factor 1-alpha

Dreissena polymorpha

3e-108

Mantle (14 and 48 days)

GO915167

cytoskeleton production and maintenance

2% of sequences identified in libraries from mantle tissue

Actin

Cyrenoida floridana

1e-82

Mantle (48 days)

GO915201

alpha tubulin

Theromyzon tessulatum

5e-40

Mantle (48 days)

GO915209

alpha tubulin a1

Mesenchytraeus solifugus

1e-09

Mantle (48 days)

GO915208

respiratory chain

1% of sequences identified in libraries from mantle tissue

  

1% of sequences identified in libraries from gill tissue

cytochrome b

Ruditapes philippinarum

8e-91

Gills (14 days)

GO915174

cytochrome c subunit I

Ruditapes philippinarum

6e-25

Mantle (14 days)

GO915173

metabolism

1% of sequences identified in libraries from mantle tissue

ADP/ATP carrier

Leishmania mexicana amazonensis

2e-05

Mantle (14 days)

GO915170

ribosomal proteins

4% of sequences identified in libraries from mantle tissue

ribosomal protein L7

Argopecten irradians

8e-03

Mantle (48 days)

GO915202

ribosomal protein L19

Crassostrea gigas

9e-21

Mantle (48 days)

GO915205

ribosomal protein L24

Danio rerio

3e-12

Mantle (14 days)

GO915172

unknown functions

8% of sequences identified in libraries from mantle tissue

SJCHGC02792 protein

Schistosoma japonicum

3e-12

Mantle (14 days)

GO915171

hypothetical protein DDBDRAFT_0167791

Dictyostelium discoideum AX4

1e-04

Mantle (14 days)

GO915168

hypothetical protein

Monodelphis domestica

2e-27

Mantle (48 days)

GO915196

similar to product in Drosophila melanogaster

Schistosoma japonicum

7e-04

Mantle (48 days)

GO915187

unknown genes

17% of sequences identified in libraries from mantle tissue

  

3% of sequences identified in libraries from gill tissue

1 sequence

  

Mantle (14 days)

GO915165

23 sequences

  

Mantle (48 days)

GO915179-86, 88-89, 91-95, 97-98, GO915200, 03-04, 06-07, 10

2 sequences

  

Gills (14 days)

GO915175-76