From: The degree of microbiome complexity influences the epithelial response to infection
Impacted pathwayb | Impact factorc | # of modulated genes (total) in Pathwayd | p-value |
---|---|---|---|
Cell cycle | 13.542 | 45 (112) | < 0.001 |
Ubiquitin mediated proteolysis | 11.305 | 22 (45) | < 0.001 |
Adherens junction | 8.788 | 29 (77) | < 0.001 |
TGF-beta signaling pathway | 7.989 | 29 (84) | 0.002 |
SNARE interactions in vesicular transport | 7.691 | 16 (36) | 0.001 |
Apoptosis | 7.513 | 30 (84) | 0.002 |
Jak-STAT signaling pathway | 6.989 | 46 (153) | 0.003 |
MAPK signaling pathway | 6.207 | 75 (273) | 0.009 |
Wnt signaling pathway | 5.208 | 42 (147) | 0.02 |
Colorectal cancer | 5.184 | 23 (77) | 0.05 |
Notch signaling pathway | 5.134 | 16 (46) | 0.03 |