Table 2 List of candidate targets of hERα.
Gene symbol | EREs | FOX | SP1 | Association to ESR1 |
|---|---|---|---|---|
AFF3 | 1 | 1 | 0 | Not yet reported |
ANXA9 | 1 | 0 | 1 | Not yet reported |
ARL3 | 1 | 1 | 0 | Not yet reported |
ARSG | 0 | 0 | 0 | Estrogen signaling |
ATRNL1 | 0 | 1 | 0 | Not yet reported |
C6orf97 | 1 | 1 | 0 | Upstream of ESR1, no association reported |
CELSR1 | 2 | 0 | 0 | Cancer signature |
CISH | 1 | 0 | 0 | Known target of ESR1 |
CXXC5 | 3 | 2 | 1 | Not yet reported |
CYP24A1 | 0 | 0 | 0 | Breast cancer signature |
DSCAM | 2 | 3 | 0 | Known target of ESR1 |
ERBB4 | 1 | 2 | 0 | Estrogen signaling |
FAM63A | 1 | 0 | 1 | Not yet reported |
FSIP1 | 1 | 1 | 0 | Not yet reported |
GREB1 | 1 | 0 | 1 | Known target of ESR1 |
IGF1R | 1 | 2 | 0 | Known target of ESR1 |
JMJD2B | 2 | 1 | 1 | Known target of ESR1 |
LMBR1 | 1 | 1 | 0 | Anterior upper body development |
MLPH | 2 | 2 | 1 | Anterior upper body development |
MYB | 1 | 1 | 0 | Known target of ESR1 |
PARD6B | 0 | 1 | 0 | Known target of ESR1 |
PDZK1 | 2 | 3 | 0 | Known target of ESR1 |
PKIB | 2 | 2 | 0 | Not yet reported |
PREX1 | 2 | 1 | 0 | Cancer signature |
PTPRG | 2 | 4 | 0 | Known target of ESR1 |
RARA | 1 | 0 | 0 | Known target of ESR1 |
SFXN2 | 1 | 1 | 0 | Not yet reported |
SGK3 | 1 | 1 | 1 | Cancer signature |
SIAH2 | 2 | 2 | 0 | Known target of ESR1 |
SLC22A5 | 1 | 1 | 0 | Cancer signature |
SLC9A3R1 | 3 | 1 | 0 | Cancer signature |
SPOCK1 | 1 | 1 | 0 | Cancer signature |
STARD10 | 1 | 1 | 0 | Breast cancer signature |
TFF1 | 1 | 1 | 1 | Known target of ESR1 |
VAV3 | 2 | 3 | 0 | Estrogen signaling |