From: Effect of CAR activation on selected metabolic pathways in normal and hyperlipidemic mouse livers
Treatment | Vehicle | TCPOBOP | Vehicle | TCPOBOP |
---|---|---|---|---|
Diet | Standard | Standard | 1% cholesterol | 1% cholesterol |
Total cholesterol (mmol/L) | 3.21 ± 1.52 | 1.91 ± 0.21* | 4.09 ± 0.80* | 2.67 ± 0.61# |
LDL-cholesterol (mmol/L) | 0.33 ± 0.05 | 0.12 ± 0.02* | 0.68 ± 0.06* | 0.34 ± 0.09# |
HDL-cholesterol (mmol/L) | 1.03 ± 0.05 | 0.81 ± 0.18* | 1.76 ± 0.39* | 1.46 ± 0.37 |
Total triglyceride (mmol/L) | 0.54 ± 0.1 | 0.82 ± 0.12* | 1.39 ± 0.43* | 1.15 ± 0.25 |
Glucose (mmol/L) | 9.67 ± 0.68 | 8.59 ± 1.73 | 12.1 ± 2.16* | 10.45 ± 1.83# |