Figure 7
From: Mitochondrial dysregulation and oxidative stress in patients with chronic kidney disease
Intracellular reactive oxygen species (ROS) and serum 8-hydroxydeoxyguanosine (8-OHdG) levels in healthy subjects (HS), chronic kidney disease (CKD IV–V) and hemodialysis (HD) patients. The histograms represent the mean ± SD of 2',7'-Dichlorodihydrofluorescein (DCF) fluorescence (A) and serum 8-OHdG levels (B) in 12 HS, 10 CKD and 14 HD patients. DCF fluorescence in PBMC, reflecting the relative ROS levels, and the serum 8-OHdG levels were higher in HD and CKD compared to HS. In addition HD patients had higher 8-OHdG levels compared to CKD.