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Table 1 Patient demographics and clinical characteristics of the training-group

From: Mitochondrial dysregulation and oxidative stress in patients with chronic kidney disease

 

healthy subjects

CKD II–III

CKD IV–V

HD

P-value

Number

8

9

10

17

/

Gender (M/F)

3/5

5/4

6/4

10/7

n.s.

Age (years)

49.37 ± 10.68

49.12 ± 9.82

51.11 ± 7.18

52.86 ± 8.63

n.s.

Cause of CKD: GN, ADPKD, renal vascular disease, unknown

/

3,2,1,3

4,2,2,2

6,4,2,5

n.s.

Time on dialysis (years)

/

/

/

3.98 ± 0.56

/

BMI (kg/m2)

22.9 ± 1.42

22.1 ± 0.92

21.3 ± 1.05

21.8 ± 1.01

p = 0.02

Systolic blood pressure (mmHg)

121 ± 3.51

135 ± 17.4

137 ± 13.22

136 ± 13.22

p = 0.05

Diastolyc blood pressure (mmHg)

72.12 ± 7.59

83.11 ± 6.23

82 ± 9.54

84 ± 10.01

p = 0.02

Total protein (g/dl)

7.02 ± 0.31

6.60 ± 0.42

5.82 ± 0.72

5.96 ± 0.36

p < 0.01

Albumin (g/dl)

4.4 ± 0.11

4.1 ± 0.24

3.93 ± 0.67

3.48 ± 0.51

p < 0.01

Ferritin (ng/ml)

87 ± 40.1

136 ± 56.1

376 ± 318.2

451 ± 283.1

p < 0.01

Hemoglobin (g/dl)

13.65 ± 1.17

12.07 ± 1.70

11.13 ± 1.01

11.48 ± 1.98

p < 0.01

  1. GN: Glomerulonephritis; ADPKD: Autosomal dominant polycystic kidney disease. Values are expressed as mean ± SD. P-values calculated by ANOVA.