From: Mitochondrial dysregulation and oxidative stress in patients with chronic kidney disease
 | healthy subjects | CKD II–III | CKD IV–V | HD | P-value |
---|---|---|---|---|---|
Number | 8 | 9 | 10 | 17 | / |
Gender (M/F) | 3/5 | 5/4 | 6/4 | 10/7 | n.s. |
Age (years) | 49.37 ± 10.68 | 49.12 ± 9.82 | 51.11 ± 7.18 | 52.86 ± 8.63 | n.s. |
Cause of CKD: GN, ADPKD, renal vascular disease, unknown | / | 3,2,1,3 | 4,2,2,2 | 6,4,2,5 | n.s. |
Time on dialysis (years) | / | / | / | 3.98 ± 0.56 | / |
BMI (kg/m2) | 22.9 ± 1.42 | 22.1 ± 0.92 | 21.3 ± 1.05 | 21.8 ± 1.01 | p = 0.02 |
Systolic blood pressure (mmHg) | 121 ± 3.51 | 135 ± 17.4 | 137 ± 13.22 | 136 ± 13.22 | p = 0.05 |
Diastolyc blood pressure (mmHg) | 72.12 ± 7.59 | 83.11 ± 6.23 | 82 ± 9.54 | 84 ± 10.01 | p = 0.02 |
Total protein (g/dl) | 7.02 ± 0.31 | 6.60 ± 0.42 | 5.82 ± 0.72 | 5.96 ± 0.36 | p < 0.01 |
Albumin (g/dl) | 4.4 ± 0.11 | 4.1 ± 0.24 | 3.93 ± 0.67 | 3.48 ± 0.51 | p < 0.01 |
Ferritin (ng/ml) | 87 ± 40.1 | 136 ± 56.1 | 376 ± 318.2 | 451 ± 283.1 | p < 0.01 |
Hemoglobin (g/dl) | 13.65 ± 1.17 | 12.07 ± 1.70 | 11.13 ± 1.01 | 11.48 ± 1.98 | p < 0.01 |