Skip to main content

Advertisement

Table 1 Top genes upregulated in CD16+ compared to CD16- Mo

From: Transcriptional profiling reveals developmental relationship and distinct biological functions of CD16+ and CD16- monocyte subsets

    CD16+ Mo AU  
Gene Symbol CD16+/CD16- Ratio p-value Mean SD GeneTitle
FCGR3A 20,1 0,000 36975 6660 Fc fragment of IgG, low affinity IIIa, receptor for (CD16)
CDKN1C 18,4 0,000 23838 5132 cyclin-dependent kinase inhibitor 1C (p57, Kip2)
MTSS1 5,7 0,000 12285 2678 metastasis suppressor 1
SIGLEC10 4,8 0,000 10657 3068 sialic acid binding Ig-like lectin 10
IFITM1 4,5 0,026 13823 10613 interferon induced transmembrane protein 1 (9–27)
HMOX1 3,5 0,000 16791 4339 heme oxygenase (decycling) 1
TAGLN 3,2 0,000 11950 3480 Transgelin
TCF7L2 3,0 0,000 16772 4608 transcription factor 7-like 2 (T-cell specific, HMG-box)
MS4A7 2,8 0,000 22645 6376 membrane-spanning 4-domains, subfamily A, member 7
CSF1R 2,8 0,000 22838 6537 colony stimulating factor 1 receptor
NAP1L1 2,8 0,000 34370 5546 nucleosome assembly protein 1-like 1
IFITM2 2,5 0,000 58835 17536 interferon induced transmembrane protein 2 (1-8D)
SOD1 2,5 0,000 11300 2491 superoxide dismutase 1
IFITM3 2,5 0,022 40793 15947 interferon induced transmembrane protein 3 (1-8U)
LST1 2,5 0,000 42904 13661 leukocyte specific transcript 1
CX3CR1 2,4 0,041 25882 11806 chemokine (C-X3-C motif) receptor 1
LILRB1 2,4 0,000 15534 4951 leukocyte immunoglobulin-like receptor, subfamily B, member 1
PSCDBP 2,3 0,000 12459 2539 pleckstrin homology, Sec7 and coiled-coil domains, binding protein
ITGAL 2,3 0,000 13269 3384 integrin, alpha L (antigen CD11A)
C6orf187 2,3 0,022 14752 5263 chromosome 6 open reading frame 187
KLF2 2,3 0,000 23783 7614 Kruppel-like factor 2 (lung)
WARS 2,3 0,000 18466 5567 tryptophanyl-tRNA synthetase
MAFB 2,3 0,000 16707 5853 v-maf musculoaponeurotic fibrosarcoma oncogene homolog B
GCH1 2,2 0,022 10956 3586 GTP cyclohydrolase 1 (dopa-responsive dystonia)
CD97 2,2 0,000 10566 3203 CD97 antigen
CTSC 2,2 0,000 10079 2619 cathepsin C
PIK3AP1 2,1 0,000 16825 4941 phosphoinositide-3-kinase adaptor protein 1
MAIL 2,1 0,000 15859 4883 molecule possessing ankyrin repeats induced by lipopolysaccharide
LYN 2,1 0,000 19388 3520 v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
BCL2A1 2,1 0,022 11110 5056 BCL2-related protein A1
PECAM1 2,0 0,000 22679 7106 platelet/endothelial cell adhesion molecule (CD31 antigen)
  1. Shown are differentially expressed genes (>2-fold higher in CD16+ compared to CD16- Mo) with the highest expression levels (>10,000 AU). AU, arbitrary units.