Figure 1
From: Molecular mechanisms of tungstate-induced pancreatic plasticity: a transcriptomics approach
Effects of tungstate administration on blood and beta cell parameters. a Glycemia evolution of healthy untreated (open circles), healthy treated (filled circles), diabetic untreated (blank squares) and diabetic treated (filled squares) rats, n = 9. b Representative images of pancreatic sections stained with insulin (magnification 20×) for HU, DU and DT.c, d The percentage of insulin (c) and Pdx-1 (d) positive cells in the islets was analyzed from the pancreas (at three different levels), n = 6. e, f Beta cell apoptosis (e) and proliferation (f) were assessed by propidium iodide and Pcna staining, respectively, n = 8–10. g, h Insulin (g) and amylase (h) serum levels at the end of the tungstate treatment, n = 8–10. ***p < 0.001 and **p < 0.01 compared to healthy untreated animals, †††p < 0.001, ††p < 0.01 and†p < 0.05 compared to diabetic untreated animals.